Chronic impairment of mitochondrial bioenergetics and β-oxidation promotes experimental AKI-to-CKD transition induced by folic acid

Recent studies suggest that mitochondrial bioenergetics and oxidative stress alterations may be common mechanisms involved in the progression of renal damage. However, the evolution of the mitochondrial alterations over time and the possible effects that their prevention could have in the progressio...

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Veröffentlicht in:	Free radical biology & medicine 2020-07, Vol.154, p.18-32
Hauptverfasser:	Aparicio-Trejo, Omar Emiliano, Avila-Rojas, Sabino Hazael, Tapia, Edilia, Rojas-Morales, Pedro, León-Contreras, Juan Carlos, Martínez-Klimova, Elena, Hernández-Pando, Rogelio, Sánchez- Lozada, Laura Gabriela, Pedraza-Chaverri, José
Format:	Artikel
Sprache:	eng
Schlagworte:	Folic acid Mitochondrial bioenergetics Mitochondrial oxidative stress N-acetyl-cysteine Renal damage progression
Online-Zugang:	Volltext
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