Antioxidant Analogue 6-Amino-2,4,5-Trimethylpyridin-3-ol Ameliorates Experimental Colitis in Mice

Background Oxidative stress has been suggested to be a factor contributing to the disease severity of inflammatory bowel disease (IBD). BJ-1108, a derivative of 6-amino-2,4,5-trimethylpyridin-3-ol, is reported to significantly inhibit the generation of reactive oxygen species (ROS) in vitro. However...

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Veröffentlicht in:	Digestive diseases and sciences 2021-04, Vol.66 (4), p.1022-1033
Hauptverfasser:	Lee, Hoyul, Lee, Joon Seop, Cho, Hyun Jung, Lee, Yu-Jeong, Kim, Eun Soo, Kim, Sung Kook, Nam, Tae-gyu, Jeong, Byeong-Seon, Kim, Jung-Ae
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antioxidants Biochemistry Body weight Colitis Dextran Diet therapy Gastroenterology Gastrointestinal diseases Hepatology Inflammation Inflammatory bowel disease Kinases Medical colleges Medical research Medicine Medicine & Public Health Medicine, Experimental Oncology Original Article Oxidative stress Permeability Protein kinases Proteins Reactive oxygen species Sulfates T cells Transplant Surgery
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