Delivery of CRISPR/Cas systems for cancer gene therapy and immunotherapy

The clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) systems are efficient and versatile gene editing tools, which offer enormous potential to treat cancer by editing genome, transcriptome or epigenome of tumor cells and/or immune cells. A large bo...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Advanced drug delivery reviews 2021-01, Vol.168, p.158-180
Hauptverfasser:	Song, Xiangrong, Liu, Chao, Wang, Ning, Huang, Hai, He, Siyan, Gong, Changyang, Wei, Yuquan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-tumor targets Cancer gene therapy Cancer immunotherapy Clinical translation CRISPR/Cas systems Delivery Non-viral vectors Viral vectors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!