G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development

The methyltransferase G9a was originally isolated as a histone methyltransferase that catalyzes the methylation of histone 3 lysine 9 (H3K9) to a dimethylated state (H3K9me2). Recent studies have revealed that G9a has multiple functions in various cells, including osteoblasts. Here, we investigated...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2020-08, Vol.137, p.115332-115332, Article 115332
Hauptverfasser:	Ideno, Hisashi, Nakashima, Kazuhisa, Komatsu, Koichiro, Araki, Ryoko, Abe, Masumi, Arai, Yoshinori, Kimura, Hiroshi, Shinkai, Yoichi, Tachibana, Makoto, Nifuji, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Core Binding Factor Alpha 1 Subunit - genetics Cranial bone Epigenetics Histone methyltransferase Histone-Lysine N-Methyltransferase Mice Osteoblasts Osteogenesis Promoter Regions, Genetic Runx2 Skull
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