A TRACER culture invasion assay to probe the impact of cancer associated fibroblasts on head and neck squamous cell carcinoma cell invasiveness

Cancer associated fibroblasts (CAFs) are a major cellular component of the tumour stroma and have been shown to promote tumour cell invasion and disease progression. CAF-cancer cell interactions are bi-directional and occur via both soluble factor dependent and extracellular matrix (ECM) remodelling...

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Veröffentlicht in:	Biomaterials science 2020-06, Vol.8 (11), p.378-394
Hauptverfasser:	Dean, Teresa, Li, Nancy T, Cadavid, Jose L, Ailles, Laurie, McGuigan, Alison P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aluminum Biological Assay Cancer Cancer-Associated Fibroblasts Cell Line, Tumor Coculture Techniques Collagen Fibroblasts Head and Neck Neoplasms - pathology Humans Hydrogels Multilayers Squamous Cell Carcinoma of Head and Neck - pathology Tumors
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