Synthesis of All-Carbon Disubstituted Bicyclo1.1.1pentanes by Iron-Catalyzed Kumada Cross-Coupling

1,3-Disubstituted bicyclo[1.1.1]pentanes (BCPs) are important motifs in drug design as surrogates for p-substituted arenes and alkynes. Access to all-carbon disubstituted BCPs via cross-coupling has to date been limited to use of the BCP as the organometallic component, which restricts scope due to...

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Veröffentlicht in:	Angewandte Chemie International Edition 2020-07, Vol.59 (29), p.11866
Hauptverfasser:	Nugent, Jeremy, Shire, Bethany R, Caputo, Dimitri F J, Pickford, Helena D, Nightingale, Frank, Houlsby, Ian T T, Mousseau, James J, Anderson, Edward A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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