SMYD2 facilitates cancer cell malignancy and xenograft tumor development through ERBB2-mediated FUT4 expression in colon cancer

The aim of this study is to assess the expression levels of SMYD2 in human tissue samples and cells of colon cancer, and further explore the potential mechanisms of SMYD2 in colon cancer progression. Quantitative PCR and Immunohistochemical (IHC) assays were performed to detect SMYD2 expression in 7...

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Veröffentlicht in:	Molecular and cellular biochemistry 2022-09, Vol.477 (9), p.2149-2159
Hauptverfasser:	Lai, Yanzong, Yang, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Apoptosis Assaying Biochemistry Biomedical and Life Sciences Cardiology Cell proliferation Colon Colon cancer Colorectal cancer ErbB-2 protein Flow cytometry Human tissues In vivo methods and tests Life Sciences Lymph nodes Malignancy Medical Biochemistry Metastases Metastasis Oncology Signal transduction Signaling Therapeutic targets Tissues Tumors Xenografts Xenotransplantation
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