DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling

Although platinum compounds are the first-line treatment for ovarian cancer, the majority of patients relapse and develop resistance to treatment. However, the mechanism underlying resistance is unclear. The goal of our study is to decipher the mechanism by which a metabolic kinase, diacylglycerol k...

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Veröffentlicht in:	Clinical cancer research 2020-07, Vol.26 (14), p.3843-3855
Hauptverfasser:	Li, Jie, Pan, Chaoyun, Boese, Austin C, Kang, JiHoon, Umano, Anna D, Magliocca, Kelly R, Yang, Wenqing, Zhang, Yu, Lonial, Sagar, Jin, Lingtao, Kang, Sumin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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