First Experience of Sutureless Redo on Mitral Valve Using Valve-in-Valve Technique: Two-Stage Implantation on a Large Animal
Sutureless implantation of the mitral valve bioprosthesis using the valve-in-valve method was performed on a large animal (sheep). According to the results of a two-stage implantation (primary implantation of a xenopericardial 26-mm framed bioprosthesis and reimplantation of the developed 23-mm biop...
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2020-04, Vol.168 (6), p.817-820 |
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creator | Barbarash, L. S. Klyshnikov, K. Yu Khaes, B. L. Halivopulo, I. K. Stasev, A. N. Krutitsky, S. S. Borisenko, D. V. Sitnikova, M. A. Ivanova, A. V. Kudryavtseva, Yu. A. Kokorin, S. G. Evtushenko, A. V. Ovcharenko, E. A. |
description | Sutureless implantation of the mitral valve bioprosthesis using the valve-in-valve method was performed on a large animal (sheep). According to the results of a two-stage implantation (primary implantation of a xenopericardial 26-mm framed bioprosthesis and reimplantation of the developed 23-mm bioprosthesis), minor changes in quantitative indicators were revealed: an increase in the transprosthetic gradient by 1.3 mm Hg and a decrease in the area of the mitral orifice by 21.6%. Considerable reduction in the intervention time by 18 min was achieved (by 40% in comparison with the primary prosthesis). The absence of adverse events in the animal and complications in the post-operative period, as well as physiological hemodynamic indicators indicate the safety of the developed medical device. |
doi_str_mv | 10.1007/s10517-020-04809-6 |
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S. ; Klyshnikov, K. Yu ; Khaes, B. L. ; Halivopulo, I. K. ; Stasev, A. N. ; Krutitsky, S. S. ; Borisenko, D. V. ; Sitnikova, M. A. ; Ivanova, A. V. ; Kudryavtseva, Yu. A. ; Kokorin, S. G. ; Evtushenko, A. V. ; Ovcharenko, E. A.</creator><creatorcontrib>Barbarash, L. S. ; Klyshnikov, K. Yu ; Khaes, B. L. ; Halivopulo, I. K. ; Stasev, A. N. ; Krutitsky, S. S. ; Borisenko, D. V. ; Sitnikova, M. A. ; Ivanova, A. V. ; Kudryavtseva, Yu. A. ; Kokorin, S. G. ; Evtushenko, A. V. ; Ovcharenko, E. A.</creatorcontrib><description>Sutureless implantation of the mitral valve bioprosthesis using the valve-in-valve method was performed on a large animal (sheep). According to the results of a two-stage implantation (primary implantation of a xenopericardial 26-mm framed bioprosthesis and reimplantation of the developed 23-mm bioprosthesis), minor changes in quantitative indicators were revealed: an increase in the transprosthetic gradient by 1.3 mm Hg and a decrease in the area of the mitral orifice by 21.6%. Considerable reduction in the intervention time by 18 min was achieved (by 40% in comparison with the primary prosthesis). The absence of adverse events in the animal and complications in the post-operative period, as well as physiological hemodynamic indicators indicate the safety of the developed medical device.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-020-04809-6</identifier><identifier>PMID: 32328943</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Animals ; Biomedical and Life Sciences ; Biomedicine ; Bioprosthesis ; Cardiopulmonary Bypass - methods ; Cell Biology ; Disease Models, Animal ; Echocardiography ; Female ; Heart Function Tests ; Heart valve diseases ; Hemodynamics - physiology ; Implants, Artificial ; Internal Medicine ; Laboratory Medicine ; Methods ; Mitral Valve - surgery ; Mitral Valve - transplantation ; Mitral Valve Stenosis - diagnosis ; Mitral Valve Stenosis - pathology ; Mitral Valve Stenosis - surgery ; Operative Time ; Pathology ; Prosthesis ; Replantation - instrumentation ; Replantation - methods ; Sheep ; Treatment Outcome</subject><ispartof>Bulletin of experimental biology and medicine, 2020-04, Vol.168 (6), p.817-820</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>COPYRIGHT 2020 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c396t-4e02a0541e3c181b94b6ca528b0fe08b56978a2e0229c47f43f7c3e0bc83d7e83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-020-04809-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-020-04809-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32328943$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barbarash, L. 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A.</creatorcontrib><title>First Experience of Sutureless Redo on Mitral Valve Using Valve-in-Valve Technique: Two-Stage Implantation on a Large Animal</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>Sutureless implantation of the mitral valve bioprosthesis using the valve-in-valve method was performed on a large animal (sheep). According to the results of a two-stage implantation (primary implantation of a xenopericardial 26-mm framed bioprosthesis and reimplantation of the developed 23-mm bioprosthesis), minor changes in quantitative indicators were revealed: an increase in the transprosthetic gradient by 1.3 mm Hg and a decrease in the area of the mitral orifice by 21.6%. Considerable reduction in the intervention time by 18 min was achieved (by 40% in comparison with the primary prosthesis). The absence of adverse events in the animal and complications in the post-operative period, as well as physiological hemodynamic indicators indicate the safety of the developed medical device.</description><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bioprosthesis</subject><subject>Cardiopulmonary Bypass - methods</subject><subject>Cell Biology</subject><subject>Disease Models, Animal</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Heart Function Tests</subject><subject>Heart valve diseases</subject><subject>Hemodynamics - physiology</subject><subject>Implants, Artificial</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Methods</subject><subject>Mitral Valve - surgery</subject><subject>Mitral Valve - transplantation</subject><subject>Mitral Valve Stenosis - diagnosis</subject><subject>Mitral Valve Stenosis - pathology</subject><subject>Mitral Valve Stenosis - surgery</subject><subject>Operative Time</subject><subject>Pathology</subject><subject>Prosthesis</subject><subject>Replantation - instrumentation</subject><subject>Replantation - methods</subject><subject>Sheep</subject><subject>Treatment Outcome</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kVtrFDEUx4NY7Fr9Aj5IQCi-pOYyl4xvS-kNtgh262vIZM_spmSSNZnxAn54M51WLIgkkOTkdw7n_P8IvWH0hFFaf0iMlqwmlFNCC0kbUj1DC1bWgkjO2XO0oJkihZTyEL1M6W560oq9QIeCCy6bQizQr3Mb04DPfuwhWvAGcOjwzTiMERykhD_DJuDg8bUdonb4i3bfAN8m67fznVhP5uAazM7bryN8xOvvgdwMegv4qt877Qc92Fwjb41XOub40tteu1fooNMuweuH8wjdnp-tTy_J6tPF1elyRYxoqoEUQLmmZcFAGCZZ2xRtZXTJZUs7oLItq6aWmmeKN6aou0J0tRFAWyPFpgYpjtD7ue4-htxgGlRvkwGXW4MwJsVFk1WqmmZC383oVjtQ1nchz20mXC0rQWlVlJJn6uQfVF4b6K0JHjqb408Sjv9K2IF2wy4FN066pKcgn0ETQ0oROrWPWar4UzGqJtfV7LrKrqt711WVk94-zDe2PWz-pDzanAExAyl_-S1EdRfG6LPm_yv7G2aLtU4</recordid><startdate>20200401</startdate><enddate>20200401</enddate><creator>Barbarash, L. 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A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>First Experience of Sutureless Redo on Mitral Valve Using Valve-in-Valve Technique: Two-Stage Implantation on a Large Animal</atitle><jtitle>Bulletin of experimental biology and medicine</jtitle><stitle>Bull Exp Biol Med</stitle><addtitle>Bull Exp Biol Med</addtitle><date>2020-04-01</date><risdate>2020</risdate><volume>168</volume><issue>6</issue><spage>817</spage><epage>820</epage><pages>817-820</pages><issn>0007-4888</issn><eissn>1573-8221</eissn><abstract>Sutureless implantation of the mitral valve bioprosthesis using the valve-in-valve method was performed on a large animal (sheep). According to the results of a two-stage implantation (primary implantation of a xenopericardial 26-mm framed bioprosthesis and reimplantation of the developed 23-mm bioprosthesis), minor changes in quantitative indicators were revealed: an increase in the transprosthetic gradient by 1.3 mm Hg and a decrease in the area of the mitral orifice by 21.6%. Considerable reduction in the intervention time by 18 min was achieved (by 40% in comparison with the primary prosthesis). The absence of adverse events in the animal and complications in the post-operative period, as well as physiological hemodynamic indicators indicate the safety of the developed medical device.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>32328943</pmid><doi>10.1007/s10517-020-04809-6</doi><tpages>4</tpages></addata></record> |
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subjects | Animals Biomedical and Life Sciences Biomedicine Bioprosthesis Cardiopulmonary Bypass - methods Cell Biology Disease Models, Animal Echocardiography Female Heart Function Tests Heart valve diseases Hemodynamics - physiology Implants, Artificial Internal Medicine Laboratory Medicine Methods Mitral Valve - surgery Mitral Valve - transplantation Mitral Valve Stenosis - diagnosis Mitral Valve Stenosis - pathology Mitral Valve Stenosis - surgery Operative Time Pathology Prosthesis Replantation - instrumentation Replantation - methods Sheep Treatment Outcome |
title | First Experience of Sutureless Redo on Mitral Valve Using Valve-in-Valve Technique: Two-Stage Implantation on a Large Animal |
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