First Experience of Sutureless Redo on Mitral Valve Using Valve-in-Valve Technique: Two-Stage Implantation on a Large Animal

Sutureless implantation of the mitral valve bioprosthesis using the valve-in-valve method was performed on a large animal (sheep). According to the results of a two-stage implantation (primary implantation of a xenopericardial 26-mm framed bioprosthesis and reimplantation of the developed 23-mm biop...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2020-04, Vol.168 (6), p.817-820
Hauptverfasser: Barbarash, L. S., Klyshnikov, K. Yu, Khaes, B. L., Halivopulo, I. K., Stasev, A. N., Krutitsky, S. S., Borisenko, D. V., Sitnikova, M. A., Ivanova, A. V., Kudryavtseva, Yu. A., Kokorin, S. G., Evtushenko, A. V., Ovcharenko, E. A.
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container_end_page 820
container_issue 6
container_start_page 817
container_title Bulletin of experimental biology and medicine
container_volume 168
creator Barbarash, L. S.
Klyshnikov, K. Yu
Khaes, B. L.
Halivopulo, I. K.
Stasev, A. N.
Krutitsky, S. S.
Borisenko, D. V.
Sitnikova, M. A.
Ivanova, A. V.
Kudryavtseva, Yu. A.
Kokorin, S. G.
Evtushenko, A. V.
Ovcharenko, E. A.
description Sutureless implantation of the mitral valve bioprosthesis using the valve-in-valve method was performed on a large animal (sheep). According to the results of a two-stage implantation (primary implantation of a xenopericardial 26-mm framed bioprosthesis and reimplantation of the developed 23-mm bioprosthesis), minor changes in quantitative indicators were revealed: an increase in the transprosthetic gradient by 1.3 mm Hg and a decrease in the area of the mitral orifice by 21.6%. Considerable reduction in the intervention time by 18 min was achieved (by 40% in comparison with the primary prosthesis). The absence of adverse events in the animal and complications in the post-operative period, as well as physiological hemodynamic indicators indicate the safety of the developed medical device.
doi_str_mv 10.1007/s10517-020-04809-6
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subjects Animals
Biomedical and Life Sciences
Biomedicine
Bioprosthesis
Cardiopulmonary Bypass - methods
Cell Biology
Disease Models, Animal
Echocardiography
Female
Heart Function Tests
Heart valve diseases
Hemodynamics - physiology
Implants, Artificial
Internal Medicine
Laboratory Medicine
Methods
Mitral Valve - surgery
Mitral Valve - transplantation
Mitral Valve Stenosis - diagnosis
Mitral Valve Stenosis - pathology
Mitral Valve Stenosis - surgery
Operative Time
Pathology
Prosthesis
Replantation - instrumentation
Replantation - methods
Sheep
Treatment Outcome
title First Experience of Sutureless Redo on Mitral Valve Using Valve-in-Valve Technique: Two-Stage Implantation on a Large Animal
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