Complement C5 Protein as a Marker of Subclinical Atherosclerosis

The mechanisms underlying early atherosclerotic plaque formation are not completely understood. Moreover, plasma biomarkers of subclinical atherosclerosis are lacking. The purpose of this study was to analyze the temporal and topologically resolved protein changes taking place in human aortas with e...

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Veröffentlicht in:	Journal of the American College of Cardiology 2020-04, Vol.75 (16), p.1926-1941
Hauptverfasser:	Martínez-López, Diego, Roldan-Montero, Raquel, García-Marqués, Fernando, Nuñez, Estefania, Jorge, Inmaculada, Camafeita, Emilio, Minguez, Pablo, Rodriguez de Cordoba, Santiago, López-Melgar, Beatriz, Lara-Pezzi, Enrique, Fernández-Ortiz, Antonio, Ibáñez, Borja, Valdivielso, Jose Manuel, Fuster, Valentín, Michel, Jean-Baptiste, Blanco-Colio, Luis Miguel, Vázquez, Jesús, Martin-Ventura, Jose Luis
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymptomatic Diseases Atherosclerosis - blood Atherosclerosis - diagnosis biomarkers Biomarkers - analysis Complement Activation Complement C5 - analysis complement system Female Humans Immunohistochemistry Male Plaque, Atherosclerotic - metabolism Plaque, Atherosclerotic - pathology proteomics Proteomics - methods subclinical atherosclerosis
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