Rapid lipidomic profiling based on ultra-high performance liquid chromatography–mass spectrometry and its application in diabetic retinopathy

Lipidomics aims to characterize lipid alteration in response to internal or external subtle perturbations in complex biological samples. Lipid abnormality is a major risk factor for many diseases. Large-scale lipidomic studies may offer new insights into the pathophysiological mechanisms of diseases...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2020-06, Vol.412 (15), p.3585-3594
Hauptverfasser:	Xuan, Qiuhui, Zheng, Fujian, Yu, Di, Ouyang, Yang, Zhao, Xinjie, Hu, Chunxiu, Xu, Guowang
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Biochemistry Biological properties Biological samples Biology Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chromatography Chromatography, High Pressure Liquid - economics Chromatography, High Pressure Liquid - methods Current Progress in Lipidomics Data acquisition Diabetes Diabetes mellitus Diabetic retinopathy Diabetic Retinopathy - blood Elution Female Food Science High performance liquid chromatography Humans Laboratory Medicine Limit of Detection Linearity Lipidomics - economics Lipidomics - methods Lipids Lipids - analysis Lipids - blood Liquid chromatography Male Mass spectra Mass spectrometry Mass Spectrometry - economics Mass Spectrometry - methods Mass spectroscopy Medical research Medicine, Experimental Middle Aged Monitoring/Environmental Analysis Precision medicine Research Paper Retinopathy Risk analysis Risk factors Scientific imaging Spectroscopy Stability analysis Time Factors
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