GPR30 expression and function in breast cancer cells are induced through a cis‑acting element targeted by ETS factors

The capacity that G protein‑coupled receptor 30 (GPR30) has demonstrated for triggering estrogen‑dependent signaling pathways has attracted the interest of breast cancer researchers; however, the reported expression profiles and functions of GPR30 in breast cancer are inconsistent. The main purpose...

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Veröffentlicht in:	Oncology reports 2020-05, Vol.43 (5), p.1669-1682
Hauptverfasser:	Segura-Bautista, David, Olivares, Aleida, Casas-González, Patricia, Bonilla, Edmundo, Salazar, Zayil, Pérez-Solis, Marco Allán
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biotechnology Biotechnology industries Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Cancer cells Cancer metastasis Cell Line, Tumor Cell Movement Cell Survival Cloning Codons Deoxyribonucleic acid DNA DNA binding proteins Down-Regulation EDTA Estrogens ETS Motif Female Fulvestrant G proteins Gene Expression Regulation, Neoplastic Growth factors Humans Identity Laboratories MCF-7 Cells Membrane proteins Membranes Metastasis Neoplasm Metastasis Pharmaceutical industry Phenols (Class of compounds) Protein kinases Proteins Receptors, Estrogen - chemistry Receptors, Estrogen - genetics Receptors, Estrogen - metabolism Receptors, G-Protein-Coupled - chemistry Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Scientific equipment industry Signal transduction Tretinoin
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