Mild and Chemoselective Thioacylation of Amines Enabled by the Nucleophilic Activation of Elemental Sulfur

A mild and chemoselective method for the thioacylation of amines using α-keto acids and elemental sulfur has been developed. The key to the success of this transformation is the nucleophilic activation of elemental sulfur by thiols such as 1-dodecanethiol. A variety of functional groups, including u...

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Veröffentlicht in:	Journal of the American Chemical Society 2020-05, Vol.142 (18), p.8130-8135
Hauptverfasser:	Saito, Masato, Murakami, Sho, Nanjo, Takeshi, Kobayashi, Yusuke, Takemoto, Yoshiji
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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