Rational Chemical Multifunctionalization of Graphene Interface Enhances Targeted Cancer Therapy

The synthesis of a drug delivery platform based on graphene was achieved through a step‐by‐step strategy of selective amine deprotection and functionalization. The multifunctional graphene platform, functionalized with indocyanine green, folic acid, and doxorubicin showed an enhanced anticancer acti...

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Veröffentlicht in:	Angewandte Chemie International Edition 2020-08, Vol.59 (33), p.14034-14039
Hauptverfasser:	Lucherelli, Matteo Andrea, Yu, Yue, Reina, Giacomo, Abellán, Gonzalo, Miyako, Eijiro, Bianco, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Antineoplastic Agents - therapeutic use Antitumor activity Cancer Cancer therapies cancer therapy carbon materials Cell Line, Tumor diazonium salts Doxorubicin Drug delivery Drug Delivery Systems Folic acid Graphene graphite Graphite - chemistry Humans multifunctionalization Neoplasms - drug therapy Phototherapy Synergistic effect Targeted cancer therapy Therapeutic applications
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