Sulfenic Acid-Mediated on-Site-Specific Immobilization of Mitochondrial-Targeted NIR Fluorescent Probe for Prolonged Tumor Imaging

Mitochondria plays pivotal roles in energy production and apoptotic pathways. Mitochondria-targeting strategy has been recognized as a promising way for cancer theranostics. Thus, spatiotemporally manipulating the prolonged retention of theranostic agents within mitochondria is considerably signific...

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Veröffentlicht in:	Analytical chemistry (Washington) 2020-05, Vol.92 (10), p.6977-6983
Hauptverfasser:	Gao, Yinjia, Sun, Rui, Zhao, Meng, Ding, Jianan, Wang, Anna, Ye, Shuyue, Zhang, Yuqi, Mao, Qiulian, Xie, Wei, Ma, Guolin, Shi, Haibin
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Apoptosis Breast Neoplasms - diagnostic imaging Cancer Carbocyanines - chemistry Carbocyanines - metabolism Carbocyanines - pharmacology Cell Line, Tumor Chemistry Female Fluorescent Dyes - chemistry Fluorescent Dyes - metabolism Fluorescent Dyes - pharmacology Fluorescent indicators Immobilization Infrared imaging Infrared Rays Medical imaging Mice Mitochondria Mitochondria - chemistry Mitochondria - drug effects Mitochondria - metabolism Molecular Structure Optical Imaging Oxidative stress Precision medicine Proteins Retention Sulfenic acid Sulfenic Acids - chemistry Sulfenic Acids - metabolism Tumors
Online-Zugang:	Volltext
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