The Utility of Rapid Atrial Pacing Immediately Post-TAVR to Predict the Need for Pacemaker Implantation

The aim of this study was to determine the utility of rapid atrial pacing immediately after transcatheter aortic valve replacement (TAVR) to predict the need for permanent pacemaker implantation (PPI). Risk stratification for patients without high-grade atrioventricular block (AVB) after TAVR is imp...

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Veröffentlicht in:JACC. Cardiovascular interventions 2020-05, Vol.13 (9), p.1046-1054
Hauptverfasser: Krishnaswamy, Amar, Sammour, Yasser, Mangieri, Antonio, Kadri, Amer, Karrthik, Antonette, Banerjee, Kinjal, Kaur, Manpreet, Giannini, Francesco, Pagliaro, Beniamino, Ancona, Marco, Pagnesi, Matteo, Laricchia, Alessandra, Weisz, Giora, Lyden, Megan, Bazarbashi, Najdat, Gad, Mohamed, Ahuja, Keerat, Mick, Stephanie, Svensson, Lars, Puri, Rishi, Reed, Grant, Rickard, John, Colombo, Antonio, Kapadia, Samir, Latib, Azeem
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container_end_page 1054
container_issue 9
container_start_page 1046
container_title JACC. Cardiovascular interventions
container_volume 13
creator Krishnaswamy, Amar
Sammour, Yasser
Mangieri, Antonio
Kadri, Amer
Karrthik, Antonette
Banerjee, Kinjal
Kaur, Manpreet
Giannini, Francesco
Pagliaro, Beniamino
Ancona, Marco
Pagnesi, Matteo
Laricchia, Alessandra
Weisz, Giora
Lyden, Megan
Bazarbashi, Najdat
Gad, Mohamed
Ahuja, Keerat
Mick, Stephanie
Svensson, Lars
Puri, Rishi
Reed, Grant
Rickard, John
Colombo, Antonio
Kapadia, Samir
Latib, Azeem
description The aim of this study was to determine the utility of rapid atrial pacing immediately after transcatheter aortic valve replacement (TAVR) to predict the need for permanent pacemaker implantation (PPI). Risk stratification for patients without high-grade atrioventricular block (AVB) after TAVR is imprecise and based on anatomic considerations, electrocardiographic characteristics, and clinical suspicion. A more reliable assessment is necessary to minimize inpatient rhythm monitoring and/or reduce unnecessary PPI. Consecutive patients undergoing TAVR at 2 centers were included. After valve implantation in patients without pacemakers who did not have complete heart block or atrial fibrillation, the temporary pacemaker was withdrawn from the right ventricle and placed in the right atrium. Rapid atrial pacing was performed from 70 to 120 beats/min, and patients were assessed for the development of Wenckebach AVB. Patients were then followed for clinical outcomes, including PPI. A total of 284 patients were included. Of these, 130 (45.8%) developed Wenckebach AVB. There was a higher rate of PPI within 30 days of TAVR among the patients who developed Wenckebach AVB (13.1% vs. 1.3%; p 
doi_str_mv 10.1016/j.jcin.2020.01.215
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Risk stratification for patients without high-grade atrioventricular block (AVB) after TAVR is imprecise and based on anatomic considerations, electrocardiographic characteristics, and clinical suspicion. A more reliable assessment is necessary to minimize inpatient rhythm monitoring and/or reduce unnecessary PPI. Consecutive patients undergoing TAVR at 2 centers were included. After valve implantation in patients without pacemakers who did not have complete heart block or atrial fibrillation, the temporary pacemaker was withdrawn from the right ventricle and placed in the right atrium. Rapid atrial pacing was performed from 70 to 120 beats/min, and patients were assessed for the development of Wenckebach AVB. Patients were then followed for clinical outcomes, including PPI. A total of 284 patients were included. Of these, 130 (45.8%) developed Wenckebach AVB. There was a higher rate of PPI within 30 days of TAVR among the patients who developed Wenckebach AVB (13.1% vs. 1.3%; p &lt; 0.001), with a negative predictive value for PPI in the group without Wenckebach AVB of 98.7%. A greater percentage of patients receiving self-expanding valves required PPI than those receiving a balloon-expandable valves (15.9% vs. 3.7%; p = 0.001), though these rates were still relatively low among patients who did not develop Wenckebach AVB (2.9% and 0.8%). Atrial pacing post-TAVR is easily performed and can help identify patients who may benefit from extended rhythm monitoring. Patients who did not develop pacing-induced Wenckebach AVB demonstrated an extremely low likelihood of PPI. 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Cardiovascular interventions</jtitle><addtitle>JACC Cardiovasc Interv</addtitle><date>2020-05-11</date><risdate>2020</risdate><volume>13</volume><issue>9</issue><spage>1046</spage><epage>1054</epage><pages>1046-1054</pages><issn>1936-8798</issn><eissn>1876-7605</eissn><abstract>The aim of this study was to determine the utility of rapid atrial pacing immediately after transcatheter aortic valve replacement (TAVR) to predict the need for permanent pacemaker implantation (PPI). Risk stratification for patients without high-grade atrioventricular block (AVB) after TAVR is imprecise and based on anatomic considerations, electrocardiographic characteristics, and clinical suspicion. A more reliable assessment is necessary to minimize inpatient rhythm monitoring and/or reduce unnecessary PPI. Consecutive patients undergoing TAVR at 2 centers were included. After valve implantation in patients without pacemakers who did not have complete heart block or atrial fibrillation, the temporary pacemaker was withdrawn from the right ventricle and placed in the right atrium. Rapid atrial pacing was performed from 70 to 120 beats/min, and patients were assessed for the development of Wenckebach AVB. Patients were then followed for clinical outcomes, including PPI. A total of 284 patients were included. Of these, 130 (45.8%) developed Wenckebach AVB. There was a higher rate of PPI within 30 days of TAVR among the patients who developed Wenckebach AVB (13.1% vs. 1.3%; p &lt; 0.001), with a negative predictive value for PPI in the group without Wenckebach AVB of 98.7%. A greater percentage of patients receiving self-expanding valves required PPI than those receiving a balloon-expandable valves (15.9% vs. 3.7%; p = 0.001), though these rates were still relatively low among patients who did not develop Wenckebach AVB (2.9% and 0.8%). Atrial pacing post-TAVR is easily performed and can help identify patients who may benefit from extended rhythm monitoring. Patients who did not develop pacing-induced Wenckebach AVB demonstrated an extremely low likelihood of PPI. [Display omitted]</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>32305392</pmid><doi>10.1016/j.jcin.2020.01.215</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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source Elsevier ScienceDirect Journals Complete; EZB-FREE-00999 freely available EZB journals
subjects atrial pacing
electrophysiology study
permanent pacemaker implantation
transcatheter aortic valve replacement
title The Utility of Rapid Atrial Pacing Immediately Post-TAVR to Predict the Need for Pacemaker Implantation
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