Aberrant DNA methylation in the PAX2 promoter is associated with Müllerian duct anomalies

Purpose Abnormalities during Müllerian duct and female reproductive tract formation during embryonic development result in Müllerian duct anomalies (MDA). Previous studies have identified a role for mutations in related genes and DNA copy number variation (CNV). However, the correlation between gene...

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Veröffentlicht in:	Archives of gynecology and obstetrics 2020-06, Vol.301 (6), p.1455-1461
Hauptverfasser:	Wang, Chao, Xing, Qiong, Song, Bing, Li, Guanjian, Xu, Zuying, Wang, Tianjuan, Chen, Yujie, Xu, Yuping, Cao, Yunxia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics Endocrinology Female Gene expression General Gynecology Gynecology Human Genetics Humans Medicine Medicine & Public Health Mullerian Ducts - abnormalities Mutation Obstetrics/Perinatology/Midwifery PAX2 Transcription Factor - genetics Uterus
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