CircRNA‐0077930 from hyperglycaemia‐stimulated vascular endothelial cell exosomes regulates senescence in vascular smooth muscle cells

Vascular smooth muscle aging leads to diabetic complications such as cardiovascular and kidney diseases or diabetic foot. Therefore, understanding the mechanism of smooth muscle cell senescence in a high‐glucose (HG) environment is essential. The purpose of this study was to determine whether and ho...

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Veröffentlicht in:	Cell biochemistry and function 2020-12, Vol.38 (8), p.1056-1068
Hauptverfasser:	Wang, Sha, Zhan, Junkun, Lin, Xiao, Wang, Yanjiao, Wang, Yi, Liu, Youshuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing Aging Bioinformatics circRNA Complications Depletion Diabetes Diabetes mellitus Endothelial cells Exosomes high‐glucose Hyperglycemia Kidney diseases L-Lactate dehydrogenase Lactate Lactate dehydrogenase Lactic acid Mercury Muscles Oxidative stress p53 Protein Senescence Smooth muscle smooth muscle cell Superoxide dismutase Umbilical cables Umbilical vein vein endothelial cell exosomes
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