Distinct HLA and non‐HLA associations in different subtypes of ANCA‐associated vasculitides in North India

Aim Antineutrophil cytoplasmic antibody‐associated vasculitis (AAV) is an autoimmune disease characterized by necrotizing small vessel vasculitis that can affect various organs and present multiple symptoms. Susceptibility to AAV is multifactorial and most likely caused by an amalgamation of genetic...

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Veröffentlicht in:	International journal of rheumatic diseases 2020-07, Vol.23 (7), p.958-965
Hauptverfasser:	Singh, Jagdeep, Sharma, Aman, Rani, Lekha, Kaur, Navchetan, Anand, Shashi, Saikia, Biman, Jha, Saket, Nada, Ritambhra, Minz, Ranjana Walker
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles ANCA‐associated vasculitis Antineutrophil cytoplasmic antibodies Autoimmune diseases Cytotoxicity Drb1 protein Environmental factors Genotyping Granulomatosis granulomatosis with polyangiitis Histocompatibility antigen HLA Inflammatory diseases Leukocytes (eosinophilic) Lymphocytes microscopic polyangiitis myeloperoxidase Polymerase chain reaction Protein-tyrosine-phosphatase Proteinase Proteinase 3 Single-nucleotide polymorphism Vasculitis Vein & artery diseases
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