Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration

Secretory proteostasis integrates protein synthesis, processing, folding and trafficking pathways that are essential for efficient cellular secretion. For the retinal pigment epithelium (RPE), secretory proteostasis is of vital importance for the maintenance of the structural and functional integrit...

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Veröffentlicht in:	Progress in retinal and eye research 2020-11, Vol.79, p.100859-100859, Article 100859
Hauptverfasser:	Paraoan, Luminita, Sharif, Umar, Carlsson, Emil, Supharattanasitthi, Wasu, Mahmud, Nur Musfirah, Kamalden, Tengku Ain, Hiscott, Paul, Jackson, Malcolm, Grierson, Ian
Format:	Artikel
Sprache:	eng
Schlagworte:	Age-related macular degeneration AMD Amyloid β Angiogenesis Apical Basolateral Cathepsins Cystatin C Cytokine Degeneration ECM Leader sequence Neurotrophic Protease inhibitors Proteases Retinal pigment epithelium RPE Secretion Secretory proteostasis
Online-Zugang:	Volltext
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