Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik)

Zaire ebolavirus (EBOV) causes Ebola virus disease (EVD), which carries a fatality rate between 25% and 90% in humans. Liver pathology is a hallmark of terminal EVD; however, little is known about temporal disease progression. We used multiplexed fluorescent immunohistochemistry and in situ hybridiz...

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Veröffentlicht in:	The American journal of pathology 2020-07, Vol.190 (7), p.1449
Hauptverfasser:	Greenberg, Alexandra, Huber, Bertrand R, Liu, David X, Logue, James P, Hischak, Amanda M W, Hart, Randy J, Abbott, Maureen, Isic, Nejra, Hisada, Yohei M, Mackman, Nigel, Bennett, Richard S, Hensley, Lisa E, Connor, John H, Crossland, Nicholas A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - analysis Ebolavirus Female Hemorrhagic Fever, Ebola - immunology Hemorrhagic Fever, Ebola - pathology Hemorrhagic Fever, Ebola - virology Host-Pathogen Interactions - physiology Liver - immunology Liver - pathology Liver - virology Longitudinal Studies Macaca mulatta Male
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