PD-L1 upregulation accompanied with epithelial–mesenchymal transition attenuates sensitivity to ATR inhibition in p53 mutant pancreatic cancer cells

Pancreatic cancer is a highly progressive malignant tumor for which there is a critical unmet need for novel therapeutic strategies. A previous study of the authors indicated that VE-821, a selective inhibitor of the ataxia-telangiectasia-mutated and rad3-related protein (ATR), has antitumor efficac...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Medical oncology (Northwood, London, England) London, England), 2020-05, Vol.37 (5), p.47-47, Article 47
Hauptverfasser:	Song, Na, Bai, Ming, Che, Xiaofang, Li, Zhi, Jing, Wei, Li, Ce, Teng, Zan, Qu, Xiujuan, Liu, Yunpeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell adhesion & migration Hematology Internal Medicine Medicine Medicine & Public Health Oncology Original Paper Pancreatic cancer Pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!