Pyridine-Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy

Development of new photosensitizers (PSs) with high photodynamic efficacy and minimal side effects is of great interest in photodynamic therapy (PDT). In this work, we reported several pyridine-embedded phenothiazinium (pyridophenothiazinium) dyes, which could be conveniently synthesized in a few sh...

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Veröffentlicht in:Journal of medicinal chemistry 2020-05, Vol.63 (9), p.4896-4907
Hauptverfasser: Xiao, Qicai, Lin, Huirong, Wu, Juan, Pang, Xin, Zhou, Quanming, Jiang, Yue, Wang, Pan, Leung, Wingnang, Lee, Hungkay, Jiang, Sheng, Yao, Shao Q, Gao, Liqian, Liu, Gang, Xu, Chuanshan
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Sprache:eng
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