First bisphosphonate hydrogelators: potential composers of biocompatible gels
Recently, investigation of hydrogels has gained ever increasing attention mostly because of their biomedical and pharmaceutical properties, and novel hydrogelators are constantly studied to find functional applications. Bisphosphonates (BPs) are well-known compounds applicable in different fields bu...
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| Veröffentlicht in: | Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2013-12, Vol.1 (45), p.6201-6212 |
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| container_end_page | 6212 |
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| container_issue | 45 |
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| container_title | Journal of materials chemistry. B, Materials for biology and medicine |
| container_volume | 1 |
| creator | Alanne, Aino-Liisa Lahtinen, Manu Löfman, Miika Turhanen, Petri Kolehmainen, Erkki Vepsäläinen, Jouko Sievänen, Elina |
| description | Recently, investigation of hydrogels has gained ever increasing attention mostly because of their biomedical and pharmaceutical properties, and novel hydrogelators are constantly studied to find functional applications. Bisphosphonates (BPs) are well-known compounds applicable in different fields but are mostly used in clinics as drugs for bone-related diseases. In this study, a novel class of BP-hydrogelators together with a BP-organogelator was found, and the gelating abilities of the compounds were studied. Several techniques to analyze the structure and the properties of the formed gels were used, including solid state
C and
P CPMAS and solution state NMR spectroscopy, IR spectroscopy, PXRD, thermoanalysis, as well as SEM. |
| doi_str_mv | 10.1039/c3tb20957a |
| format | Article |
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C and
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C and
P CPMAS and solution state NMR spectroscopy, IR spectroscopy, PXRD, thermoanalysis, as well as SEM.</description><subject>Biocompatibility</subject><subject>Biology</subject><subject>Biomedical materials</subject><subject>Gels</subject><subject>Hydrogels</subject><subject>Infrared radiation</subject><subject>NMR spectroscopy</subject><subject>Spectroscopy</subject><issn>2050-750X</issn><issn>2050-7518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqFkE1LAzEQhoMottRe_AGyRxFW89Fkd7yJWBUqXhS8LclmYld2mzVJD_33bmmtRweGmYFn3sNDyDmj14wKuKlFMpyCLPQRGXMqaV5IVh4fdvoxItMYv-hQJVOlmJ2SkeBcMQViTF7mTYgpM03sl37bK50wW25s8J_Y6uRDvM16n3CVGt1mte96HzHEzLvhyW9vnRrTYjbg8YycON1GnO7nhLzPH97un_LF6-Pz_d0irwWnKQfDbTFTTDpVc-4cQwdSSnBQMAvUAKIFRy0DARQFzLBwUDpqpDWKIooJudzl9sF_rzGmqmtijW2rV-jXseKiLFTJAOBflKmCSSiFVAN6tUPr4GMM6Ko-NJ0Om4rRaiu7-pM9wBf73LXp0B7QX7XiB-LzexA</recordid><startdate>20131207</startdate><enddate>20131207</enddate><creator>Alanne, Aino-Liisa</creator><creator>Lahtinen, Manu</creator><creator>Löfman, Miika</creator><creator>Turhanen, Petri</creator><creator>Kolehmainen, Erkki</creator><creator>Vepsäläinen, Jouko</creator><creator>Sievänen, Elina</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>20131207</creationdate><title>First bisphosphonate hydrogelators: potential composers of biocompatible gels</title><author>Alanne, Aino-Liisa ; Lahtinen, Manu ; Löfman, Miika ; Turhanen, Petri ; Kolehmainen, Erkki ; Vepsäläinen, Jouko ; Sievänen, Elina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c320t-9b2d74615f6c22ff1ef95559f971d90b9eed9f0d19390e394e7f98f0b5db60ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Biocompatibility</topic><topic>Biology</topic><topic>Biomedical materials</topic><topic>Gels</topic><topic>Hydrogels</topic><topic>Infrared radiation</topic><topic>NMR spectroscopy</topic><topic>Spectroscopy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alanne, Aino-Liisa</creatorcontrib><creatorcontrib>Lahtinen, Manu</creatorcontrib><creatorcontrib>Löfman, Miika</creatorcontrib><creatorcontrib>Turhanen, Petri</creatorcontrib><creatorcontrib>Kolehmainen, Erkki</creatorcontrib><creatorcontrib>Vepsäläinen, Jouko</creatorcontrib><creatorcontrib>Sievänen, Elina</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of materials chemistry. B, Materials for biology and medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alanne, Aino-Liisa</au><au>Lahtinen, Manu</au><au>Löfman, Miika</au><au>Turhanen, Petri</au><au>Kolehmainen, Erkki</au><au>Vepsäläinen, Jouko</au><au>Sievänen, Elina</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>First bisphosphonate hydrogelators: potential composers of biocompatible gels</atitle><jtitle>Journal of materials chemistry. B, Materials for biology and medicine</jtitle><addtitle>J Mater Chem B</addtitle><date>2013-12-07</date><risdate>2013</risdate><volume>1</volume><issue>45</issue><spage>6201</spage><epage>6212</epage><pages>6201-6212</pages><issn>2050-750X</issn><eissn>2050-7518</eissn><abstract>Recently, investigation of hydrogels has gained ever increasing attention mostly because of their biomedical and pharmaceutical properties, and novel hydrogelators are constantly studied to find functional applications. Bisphosphonates (BPs) are well-known compounds applicable in different fields but are mostly used in clinics as drugs for bone-related diseases. In this study, a novel class of BP-hydrogelators together with a BP-organogelator was found, and the gelating abilities of the compounds were studied. Several techniques to analyze the structure and the properties of the formed gels were used, including solid state
C and
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| fulltext | fulltext |
| identifier | ISSN: 2050-750X |
| ispartof | Journal of materials chemistry. B, Materials for biology and medicine, 2013-12, Vol.1 (45), p.6201-6212 |
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| language | eng |
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| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Biocompatibility Biology Biomedical materials Gels Hydrogels Infrared radiation NMR spectroscopy Spectroscopy |
| title | First bisphosphonate hydrogelators: potential composers of biocompatible gels |
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