Functionalized Pluronic-b-poly(ε-caprolactone) based nanocarriers of paclitaxel: solubilization, antiproliferative efficacy and in vivo pharmaceutic kinetics

Novel nanocarriers for paclitaxel (PTX) were developed based on Pluronic-b-poly(ε-caprolactone) bearing pendant benzyl-oxycarbonylmethyl (BOM) groups and carboxyl groups (Pluronic-b-P(CL-co-BCL), FB)/(Pluronic-b-P(CL-co-CCL), FC). The formation and the physicochemical properties of paclitaxel-loaded...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2015-05, Vol.3 (18), p.3685-3694
Hauptverfasser:	Du, Zhengzhen, Zhang, Yan, Xu, Heng, Lang, Meidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiproliferatives Compatibility Computing time Interaction parameters Jewelry Micelles Nanostructure Solubilization
Online-Zugang:	Volltext
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