Synthetic glycopolymers as modulators of protein aggregation: influences of chemical composition, topology and concentration

Novel drug excipients are required to achieve stable formulations of protein drug candidates. Synthetic glycopolymers have been shown in some cases to improve protein formulation stability, although their structure-function relationship remains unknown. Here we report the synthesis of linear or 4-ar...

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Veröffentlicht in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2018, Vol.6 (7), p.1044-1054
Hauptverfasser: Madeira do O, J, Mastrotto, F, Francini, N, Allen, S, van der Walle, C F, Stolnik, S, Mantovani, G
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Sprache:eng
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