Src mediates β-adrenergic receptor induced YAP tyrosine phosphorylation

The Hippo pathway is a newly identified pathway and evolutionarily conserved from flies to humans mainly regulating cell proliferation. Transcriptional co-activator Yes-associated protein (YAP) functions as a major downstream effector and key node of the Hippo pathway. Phosphorylation of YAP is crit...

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Veröffentlicht in:	Science China. Life sciences 2020-05, Vol.63 (5), p.697-705
Hauptverfasser:	Wang, Wenjing, Li, Wenqi, Liu, Kai, Niu, Xiaodou, Guan, Kaihang, Jiang, Yunqi, Li, Zijian, Dong, Erdan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic receptors Biomedical and Life Sciences Cell growth Cell proliferation G protein-coupled receptors Kinases Life Sciences Phosphorylation Protein-tyrosine kinase Research Paper Src protein Transcription Yes-associated protein
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