Binding and Metabolism of Brominated Flame Retardant β-1,2-Dibromo-4-(1,2-dibromoethyl)cyclohexane in Human Microsomal P450 Enzymes: Insights from Computational Studies

The emerging brominated flame retardant, 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (TBECH), has recently attracted strong interest due to its extensive detection in the environment and potential toxicological effects on humans. Previous experiments have shown that the technical mixture of TBECH an...

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Veröffentlicht in:Chemical research in toxicology 2020-06, Vol.33 (6), p.1487-1496
Hauptverfasser: Ma, Guangcai, Yu, Haiying, Han, Cenyang, Jia, Yue, Wei, Xiaoxuan, Wang, Zhiguo
Format: Artikel
Sprache:eng
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