Novel electrocardiography parameter for paroxysmal atrial fibrillation in acute ischaemic stroke patients: P wave peak time
IntroductionIn this study, we aimed to investigate the usefulness of P wave peak time (PWPT), a novel ECG parameter, in patients who were diagnosed with acute ischaemic stroke (IS) and had paroxysmal atrial fibrillation (PAF) on Holter monitoring.Materials and methodsIn this retrospective cohort stu...
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description | IntroductionIn this study, we aimed to investigate the usefulness of P wave peak time (PWPT), a novel ECG parameter, in patients who were diagnosed with acute ischaemic stroke (IS) and had paroxysmal atrial fibrillation (PAF) on Holter monitoring.Materials and methodsIn this retrospective cohort study, we included 90 consecutive patients with acute IS who were admitted to our hospital between January 2017 and July 2019. PWPT was described as the time from the beginning of the P wave to its peak, and it was measured from leads DII and VI. The PAF diagnosis was confirmed if it was detected on the ECG during palpitation or in rhythm during the Holter recordings.ResultsIn this study, 34 (37.7%) patients with acute IS were diagnosed with PAF. In multivariate analyses, the independent predictors of PAF were age, PWPT in lead VI and PWPT in lead DII (OR: 1.34, 95% CI 1.15 to 1.56; p |
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PWPT was described as the time from the beginning of the P wave to its peak, and it was measured from leads DII and VI. The PAF diagnosis was confirmed if it was detected on the ECG during palpitation or in rhythm during the Holter recordings.ResultsIn this study, 34 (37.7%) patients with acute IS were diagnosed with PAF. In multivariate analyses, the independent predictors of PAF were age, PWPT in lead VI and PWPT in lead DII (OR: 1.34, 95% CI 1.15 to 1.56; p<0.001). A receiver operating curve analysis demonstrated that area under the curve values for PWPT in lead DII for PAF were 0.88 (95% CI 0.81 to 0.95, p<0.001). The cut-off value for PWPT in lead DII in predicting PAF was 68.5 ms with a sensitivity of 82.4% and a specificity of 75.0%.ConclusionTo the best of our knowledge, this is the first study to demonstrate a significant relationship between PWPT in lead DII and PAF among patients with acute IS.</description><identifier>ISSN: 0032-5473</identifier><identifier>EISSN: 1469-0756</identifier><identifier>DOI: 10.1136/postgradmedj-2020-137540</identifier><identifier>PMID: 32234836</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Blood ; Cardiac arrhythmia ; Cardiovascular disease ; Carotid arteries ; Coronary vessels ; Diabetes ; Electrocardiography ; Hospitals ; Hypertension ; Laboratories ; Morphology ; Software ; Stroke ; Variables</subject><ispartof>Postgraduate medical journal, 2020-10, Vol.96 (1140), p.584-588</ispartof><rights>Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2020 Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b387t-2c6df2e69d8ef05ba24dab1ac6ab1dd11216714476a610958c85cfc54899e2f03</citedby><cites>FETCH-LOGICAL-b387t-2c6df2e69d8ef05ba24dab1ac6ab1dd11216714476a610958c85cfc54899e2f03</cites><orcidid>0000-0003-0268-9641 ; 0000-0001-8188-5020</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32234836$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Öz, Ahmet</creatorcontrib><creatorcontrib>Cinar, Tufan</creatorcontrib><creatorcontrib>Kızılto Güler, Cansu</creatorcontrib><creatorcontrib>Efe, Süleyman Çağan</creatorcontrib><creatorcontrib>Emre, Ufuk</creatorcontrib><creatorcontrib>Karabağ, Turgut</creatorcontrib><creatorcontrib>Ayça, Burak</creatorcontrib><title>Novel electrocardiography parameter for paroxysmal atrial fibrillation in acute ischaemic stroke patients: P wave peak time</title><title>Postgraduate medical journal</title><addtitle>Postgrad Med J</addtitle><description>IntroductionIn this study, we aimed to investigate the usefulness of P wave peak time (PWPT), a novel ECG parameter, in patients who were diagnosed with acute ischaemic stroke (IS) and had paroxysmal atrial fibrillation (PAF) on Holter monitoring.Materials and methodsIn this retrospective cohort study, we included 90 consecutive patients with acute IS who were admitted to our hospital between January 2017 and July 2019. PWPT was described as the time from the beginning of the P wave to its peak, and it was measured from leads DII and VI. The PAF diagnosis was confirmed if it was detected on the ECG during palpitation or in rhythm during the Holter recordings.ResultsIn this study, 34 (37.7%) patients with acute IS were diagnosed with PAF. In multivariate analyses, the independent predictors of PAF were age, PWPT in lead VI and PWPT in lead DII (OR: 1.34, 95% CI 1.15 to 1.56; p<0.001). A receiver operating curve analysis demonstrated that area under the curve values for PWPT in lead DII for PAF were 0.88 (95% CI 0.81 to 0.95, p<0.001). The cut-off value for PWPT in lead DII in predicting PAF was 68.5 ms with a sensitivity of 82.4% and a specificity of 75.0%.ConclusionTo the best of our knowledge, this is the first study to demonstrate a significant relationship between PWPT in lead DII and PAF among patients with acute IS.</description><subject>Blood</subject><subject>Cardiac arrhythmia</subject><subject>Cardiovascular disease</subject><subject>Carotid arteries</subject><subject>Coronary vessels</subject><subject>Diabetes</subject><subject>Electrocardiography</subject><subject>Hospitals</subject><subject>Hypertension</subject><subject>Laboratories</subject><subject>Morphology</subject><subject>Software</subject><subject>Stroke</subject><subject>Variables</subject><issn>0032-5473</issn><issn>1469-0756</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkc1u1DAUhS0EokPhFZClbtiE-i-Oww5VLVSqgAWsrRvnhnqaxMF22o54eTyaFlWs2PjK9nfOPdIhhHL2nnOpT5eQ8s8I_YT9thJMsIrLplbsGdlwpduKNbV-TjaMSVHVqpFH5FVKW8YKpfhLciSFkMpIvSG_v4RbHCmO6HIMDmLvQ3Fernd0gQgTZox0CHF_C_e7NMFIIUdfxuC76McRsg8z9TMFt2akPrlrwMk7morhDRZh9jjn9IF-o3dwWx4Qbmj2E74mLwYYE755mMfkx8X597PP1dXXT5dnH6-qTpomV8LpfhCo297gwOoOhOqh4-B0Ofuec8F1w5VqNGjO2to4U7vB1cq0LYqByWPy7uC7xPBrxZTtVFJiiT5jWJMV0tSNUK3WBT35B92GNc4lnRVKmaZlRu4NzYFyMaQUcbBL9BPEneXM7guyTwuy-4LsoaAiffuwYO3K51_hYyMFkAegm7b_b_sHwq-jDw</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Öz, Ahmet</creator><creator>Cinar, Tufan</creator><creator>Kızılto Güler, Cansu</creator><creator>Efe, Süleyman Çağan</creator><creator>Emre, Ufuk</creator><creator>Karabağ, Turgut</creator><creator>Ayça, Burak</creator><general>Oxford University Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0268-9641</orcidid><orcidid>https://orcid.org/0000-0001-8188-5020</orcidid></search><sort><creationdate>20201001</creationdate><title>Novel electrocardiography parameter for paroxysmal atrial fibrillation in acute ischaemic stroke patients: P wave peak time</title><author>Öz, Ahmet ; Cinar, Tufan ; Kızılto Güler, Cansu ; Efe, Süleyman Çağan ; Emre, Ufuk ; Karabağ, Turgut ; Ayça, Burak</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b387t-2c6df2e69d8ef05ba24dab1ac6ab1dd11216714476a610958c85cfc54899e2f03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Blood</topic><topic>Cardiac arrhythmia</topic><topic>Cardiovascular disease</topic><topic>Carotid arteries</topic><topic>Coronary vessels</topic><topic>Diabetes</topic><topic>Electrocardiography</topic><topic>Hospitals</topic><topic>Hypertension</topic><topic>Laboratories</topic><topic>Morphology</topic><topic>Software</topic><topic>Stroke</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Öz, Ahmet</creatorcontrib><creatorcontrib>Cinar, Tufan</creatorcontrib><creatorcontrib>Kızılto Güler, Cansu</creatorcontrib><creatorcontrib>Efe, Süleyman Çağan</creatorcontrib><creatorcontrib>Emre, Ufuk</creatorcontrib><creatorcontrib>Karabağ, Turgut</creatorcontrib><creatorcontrib>Ayça, Burak</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Postgraduate medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Öz, Ahmet</au><au>Cinar, Tufan</au><au>Kızılto Güler, Cansu</au><au>Efe, Süleyman Çağan</au><au>Emre, Ufuk</au><au>Karabağ, Turgut</au><au>Ayça, Burak</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel electrocardiography parameter for paroxysmal atrial fibrillation in acute ischaemic stroke patients: P wave peak time</atitle><jtitle>Postgraduate medical journal</jtitle><addtitle>Postgrad Med J</addtitle><date>2020-10-01</date><risdate>2020</risdate><volume>96</volume><issue>1140</issue><spage>584</spage><epage>588</epage><pages>584-588</pages><issn>0032-5473</issn><eissn>1469-0756</eissn><abstract>IntroductionIn this study, we aimed to investigate the usefulness of P wave peak time (PWPT), a novel ECG parameter, in patients who were diagnosed with acute ischaemic stroke (IS) and had paroxysmal atrial fibrillation (PAF) on Holter monitoring.Materials and methodsIn this retrospective cohort study, we included 90 consecutive patients with acute IS who were admitted to our hospital between January 2017 and July 2019. PWPT was described as the time from the beginning of the P wave to its peak, and it was measured from leads DII and VI. The PAF diagnosis was confirmed if it was detected on the ECG during palpitation or in rhythm during the Holter recordings.ResultsIn this study, 34 (37.7%) patients with acute IS were diagnosed with PAF. In multivariate analyses, the independent predictors of PAF were age, PWPT in lead VI and PWPT in lead DII (OR: 1.34, 95% CI 1.15 to 1.56; p<0.001). A receiver operating curve analysis demonstrated that area under the curve values for PWPT in lead DII for PAF were 0.88 (95% CI 0.81 to 0.95, p<0.001). The cut-off value for PWPT in lead DII in predicting PAF was 68.5 ms with a sensitivity of 82.4% and a specificity of 75.0%.ConclusionTo the best of our knowledge, this is the first study to demonstrate a significant relationship between PWPT in lead DII and PAF among patients with acute IS.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>32234836</pmid><doi>10.1136/postgradmedj-2020-137540</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-0268-9641</orcidid><orcidid>https://orcid.org/0000-0001-8188-5020</orcidid></addata></record> |
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subjects | Blood Cardiac arrhythmia Cardiovascular disease Carotid arteries Coronary vessels Diabetes Electrocardiography Hospitals Hypertension Laboratories Morphology Software Stroke Variables |
title | Novel electrocardiography parameter for paroxysmal atrial fibrillation in acute ischaemic stroke patients: P wave peak time |
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