Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

The therapeutic response to immune checkpoint blockade (ICB) is highly variable, not only between different cancers but also between patients with the same cancer type. The biological mechanisms underlying these differences in response are incompletely understood. Identifying correlates in patient t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature protocols 2020-05, Vol.15 (5), p.1628-1648
Hauptverfasser:	Zemek, Rachael M., Fear, Vanessa S., Forbes, Cath, de Jong, Emma, Casey, Thomas H., Boon, Louis, Lassmann, Timo, Bosco, Anthony, Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/767/70 631/250/580 631/67/327 692/308/1426 Analysis Analytical Chemistry Animal models Animals Antineoplastic Agents, Immunological Biological Techniques Biomedical and Life Sciences Biotechnology Cancer Care and treatment Cell Line, Tumor Cell suspensions Computational Biology/Bioinformatics Drug Screening Assays, Antitumor Female Flow cytometry Immune checkpoint Immune response Immunohistochemistry Inoculation Life Sciences Mice Mice, Inbred BALB C Microarrays Neoplasms, Experimental Organic Chemistry Patient outcomes Physiological aspects Protocol Ribonucleic acid RNA Tumor cell lines Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!