Left ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5‐year follow‐up
Background Small retrospective studies reported that left ventricular (LV) pacing is likely to preserve LV function in children with isolated congenital complete atrioventricular block (CCAVB). The aim of this study was to prospectively evaluate LV contractility and synchrony in a cohort of neonates...
Gespeichert in:
| Veröffentlicht in: | Pacing and clinical electrophysiology 2020-06, Vol.43 (6), p.535-541 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 541 |
|---|---|
| container_issue | 6 |
| container_start_page | 535 |
| container_title | Pacing and clinical electrophysiology |
| container_volume | 43 |
| creator | Silvetti, Massimo Stefano Muzi, Giulia Unolt, Marta D'Anna, Carolina Saputo, Fabio Anselmo Di Mambro, Corrado Albanese, Sonia Ammirati, Antonio Ravà, Lucilla Drago, Fabrizio |
| description | Background
Small retrospective studies reported that left ventricular (LV) pacing is likely to preserve LV function in children with isolated congenital complete atrioventricular block (CCAVB). The aim of this study was to prospectively evaluate LV contractility and synchrony in a cohort of neonates/infants at pacemaker implantation and follow‐up.
Methods
Patients with CCAVB who underwent LV pacing were evaluated with electrocardiogram and echocardiogram in a single‐center, prospective study. Data were collected at implantation, at 1‐month and every year of follow‐up, up to 5 years. LV ventricular dimensions (diameters and volumes), systolic function (ejection fraction [EF] and global longitudinal strain [GLS]), and synchrony were evaluated. Data are reported as median (25th‐75th centiles).
Results
Twenty consecutive patients with CCAVB underwent pacemaker implantation (12 single‐chamber pacemaker [VVIR] and eight dual‐chamber pacemaker [DDD]) with epicardial leads: 17 on the LV apex and three on the free wall. Age at implantation was 0.3 months (1 day‐4.5 months). Patients showed good clinical status, normal LV dimensions, preserved systolic function, and synchrony at 60 (30‐60) months follow‐up. EF increased to normal values in patients with preimplantation EF |
| doi_str_mv | 10.1111/pace.13908 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2385268122</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2385268122</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3938-d6c6b334bf1f50403858e5740da7799582fca152261bdbba144da4501a2e91de3</originalsourceid><addsrcrecordid>eNp9kc1q3DAQx0VoSTabXvoARdBLUnCi0Yct9xaW7QcYmkOaq5BlqXHwSlvJ7uJbIC_QZ-yTVMmmPfTQuYiB3_xm0B-h10DOIdfFVht7Dqwm8gAtQHBSSBD1C7QgwKtCMlkfoeOU7gghJeHiEB0xShkDCgv00Fg34h_Wj7E306AjPm1uznBW9v4b7j32dteG6BPWvsu9035M7_Ha3AasU7IpbfIsDg43NzjNaQxDb7CbvBn74J-G0uzNbQx-xnrE4tf9z9nmNS4MQ9jlbtqeoJdOD8m-en6X6OuH9fXqU9F8-fh5ddkUhtVMFl1pypYx3jpwgnDCpJBWVJx0uqrqWkjqjAZBaQlt17YaOO80FwQ0tTV0li3R6d67jeH7ZNOoNn0ydhi0t2FKimYjLSXkz1mit_-gd2GKPl-nKAdGKyI4z9S7PWViSClap7ax3-g4KyDqMRr1GI16iibDb56VU7ux3V_0TxYZgD2w6wc7_0elri5X6730N1Cfmo0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2413270544</pqid></control><display><type>article</type><title>Left ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5‐year follow‐up</title><source>Wiley Online Library - AutoHoldings Journals</source><creator>Silvetti, Massimo Stefano ; Muzi, Giulia ; Unolt, Marta ; D'Anna, Carolina ; Saputo, Fabio Anselmo ; Di Mambro, Corrado ; Albanese, Sonia ; Ammirati, Antonio ; Ravà, Lucilla ; Drago, Fabrizio</creator><creatorcontrib>Silvetti, Massimo Stefano ; Muzi, Giulia ; Unolt, Marta ; D'Anna, Carolina ; Saputo, Fabio Anselmo ; Di Mambro, Corrado ; Albanese, Sonia ; Ammirati, Antonio ; Ravà, Lucilla ; Drago, Fabrizio</creatorcontrib><description>Background
Small retrospective studies reported that left ventricular (LV) pacing is likely to preserve LV function in children with isolated congenital complete atrioventricular block (CCAVB). The aim of this study was to prospectively evaluate LV contractility and synchrony in a cohort of neonates/infants at pacemaker implantation and follow‐up.
Methods
Patients with CCAVB who underwent LV pacing were evaluated with electrocardiogram and echocardiogram in a single‐center, prospective study. Data were collected at implantation, at 1‐month and every year of follow‐up, up to 5 years. LV ventricular dimensions (diameters and volumes), systolic function (ejection fraction [EF] and global longitudinal strain [GLS]), and synchrony were evaluated. Data are reported as median (25th‐75th centiles).
Results
Twenty consecutive patients with CCAVB underwent pacemaker implantation (12 single‐chamber pacemaker [VVIR] and eight dual‐chamber pacemaker [DDD]) with epicardial leads: 17 on the LV apex and three on the free wall. Age at implantation was 0.3 months (1 day‐4.5 months). Patients showed good clinical status, normal LV dimensions, preserved systolic function, and synchrony at 60 (30‐60) months follow‐up. EF increased to normal values in patients with preimplantation EF <50%. Presence of antibodies and pacing mode (DDD vs VVIR) had no impact on the outcome.
Conclusions
LV pacing preserved LV systolic function and synchrony in neonates and infants with CCAVB at 5‐year follow‐up. LV EF improved in patients with low preimplantation EF. Pacing mode or the presence of autoantibodies did not demonstrated an impact on LV contractility and synchrony.</description><identifier>ISSN: 0147-8389</identifier><identifier>EISSN: 1540-8159</identifier><identifier>DOI: 10.1111/pace.13908</identifier><identifier>PMID: 32233121</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>alternative pacing sites ; Autoantibodies ; cardiac pacing ; children ; congenital atrioventricular block ; Contractility ; Echocardiography ; EKG ; Heart ; Heart failure ; Infants ; Neonates ; Pacemakers ; Ventricle</subject><ispartof>Pacing and clinical electrophysiology, 2020-06, Vol.43 (6), p.535-541</ispartof><rights>2020 The Authors. published by Wiley Periodicals LLC</rights><rights>2020 The Authors. Pacing and Clinical Electrophysiology published by Wiley Periodicals, Inc.</rights><rights>2020. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3938-d6c6b334bf1f50403858e5740da7799582fca152261bdbba144da4501a2e91de3</citedby><cites>FETCH-LOGICAL-c3938-d6c6b334bf1f50403858e5740da7799582fca152261bdbba144da4501a2e91de3</cites><orcidid>0000-0001-9284-5972</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fpace.13908$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fpace.13908$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32233121$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silvetti, Massimo Stefano</creatorcontrib><creatorcontrib>Muzi, Giulia</creatorcontrib><creatorcontrib>Unolt, Marta</creatorcontrib><creatorcontrib>D'Anna, Carolina</creatorcontrib><creatorcontrib>Saputo, Fabio Anselmo</creatorcontrib><creatorcontrib>Di Mambro, Corrado</creatorcontrib><creatorcontrib>Albanese, Sonia</creatorcontrib><creatorcontrib>Ammirati, Antonio</creatorcontrib><creatorcontrib>Ravà, Lucilla</creatorcontrib><creatorcontrib>Drago, Fabrizio</creatorcontrib><title>Left ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5‐year follow‐up</title><title>Pacing and clinical electrophysiology</title><addtitle>Pacing Clin Electrophysiol</addtitle><description>Background
Small retrospective studies reported that left ventricular (LV) pacing is likely to preserve LV function in children with isolated congenital complete atrioventricular block (CCAVB). The aim of this study was to prospectively evaluate LV contractility and synchrony in a cohort of neonates/infants at pacemaker implantation and follow‐up.
Methods
Patients with CCAVB who underwent LV pacing were evaluated with electrocardiogram and echocardiogram in a single‐center, prospective study. Data were collected at implantation, at 1‐month and every year of follow‐up, up to 5 years. LV ventricular dimensions (diameters and volumes), systolic function (ejection fraction [EF] and global longitudinal strain [GLS]), and synchrony were evaluated. Data are reported as median (25th‐75th centiles).
Results
Twenty consecutive patients with CCAVB underwent pacemaker implantation (12 single‐chamber pacemaker [VVIR] and eight dual‐chamber pacemaker [DDD]) with epicardial leads: 17 on the LV apex and three on the free wall. Age at implantation was 0.3 months (1 day‐4.5 months). Patients showed good clinical status, normal LV dimensions, preserved systolic function, and synchrony at 60 (30‐60) months follow‐up. EF increased to normal values in patients with preimplantation EF <50%. Presence of antibodies and pacing mode (DDD vs VVIR) had no impact on the outcome.
Conclusions
LV pacing preserved LV systolic function and synchrony in neonates and infants with CCAVB at 5‐year follow‐up. LV EF improved in patients with low preimplantation EF. Pacing mode or the presence of autoantibodies did not demonstrated an impact on LV contractility and synchrony.</description><subject>alternative pacing sites</subject><subject>Autoantibodies</subject><subject>cardiac pacing</subject><subject>children</subject><subject>congenital atrioventricular block</subject><subject>Contractility</subject><subject>Echocardiography</subject><subject>EKG</subject><subject>Heart</subject><subject>Heart failure</subject><subject>Infants</subject><subject>Neonates</subject><subject>Pacemakers</subject><subject>Ventricle</subject><issn>0147-8389</issn><issn>1540-8159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><recordid>eNp9kc1q3DAQx0VoSTabXvoARdBLUnCi0Yct9xaW7QcYmkOaq5BlqXHwSlvJ7uJbIC_QZ-yTVMmmPfTQuYiB3_xm0B-h10DOIdfFVht7Dqwm8gAtQHBSSBD1C7QgwKtCMlkfoeOU7gghJeHiEB0xShkDCgv00Fg34h_Wj7E306AjPm1uznBW9v4b7j32dteG6BPWvsu9035M7_Ha3AasU7IpbfIsDg43NzjNaQxDb7CbvBn74J-G0uzNbQx-xnrE4tf9z9nmNS4MQ9jlbtqeoJdOD8m-en6X6OuH9fXqU9F8-fh5ddkUhtVMFl1pypYx3jpwgnDCpJBWVJx0uqrqWkjqjAZBaQlt17YaOO80FwQ0tTV0li3R6d67jeH7ZNOoNn0ydhi0t2FKimYjLSXkz1mit_-gd2GKPl-nKAdGKyI4z9S7PWViSClap7ax3-g4KyDqMRr1GI16iibDb56VU7ux3V_0TxYZgD2w6wc7_0elri5X6730N1Cfmo0</recordid><startdate>202006</startdate><enddate>202006</enddate><creator>Silvetti, Massimo Stefano</creator><creator>Muzi, Giulia</creator><creator>Unolt, Marta</creator><creator>D'Anna, Carolina</creator><creator>Saputo, Fabio Anselmo</creator><creator>Di Mambro, Corrado</creator><creator>Albanese, Sonia</creator><creator>Ammirati, Antonio</creator><creator>Ravà, Lucilla</creator><creator>Drago, Fabrizio</creator><general>Wiley Subscription Services, Inc</general><scope>24P</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9284-5972</orcidid></search><sort><creationdate>202006</creationdate><title>Left ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5‐year follow‐up</title><author>Silvetti, Massimo Stefano ; Muzi, Giulia ; Unolt, Marta ; D'Anna, Carolina ; Saputo, Fabio Anselmo ; Di Mambro, Corrado ; Albanese, Sonia ; Ammirati, Antonio ; Ravà, Lucilla ; Drago, Fabrizio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3938-d6c6b334bf1f50403858e5740da7799582fca152261bdbba144da4501a2e91de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>alternative pacing sites</topic><topic>Autoantibodies</topic><topic>cardiac pacing</topic><topic>children</topic><topic>congenital atrioventricular block</topic><topic>Contractility</topic><topic>Echocardiography</topic><topic>EKG</topic><topic>Heart</topic><topic>Heart failure</topic><topic>Infants</topic><topic>Neonates</topic><topic>Pacemakers</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silvetti, Massimo Stefano</creatorcontrib><creatorcontrib>Muzi, Giulia</creatorcontrib><creatorcontrib>Unolt, Marta</creatorcontrib><creatorcontrib>D'Anna, Carolina</creatorcontrib><creatorcontrib>Saputo, Fabio Anselmo</creatorcontrib><creatorcontrib>Di Mambro, Corrado</creatorcontrib><creatorcontrib>Albanese, Sonia</creatorcontrib><creatorcontrib>Ammirati, Antonio</creatorcontrib><creatorcontrib>Ravà, Lucilla</creatorcontrib><creatorcontrib>Drago, Fabrizio</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Pacing and clinical electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silvetti, Massimo Stefano</au><au>Muzi, Giulia</au><au>Unolt, Marta</au><au>D'Anna, Carolina</au><au>Saputo, Fabio Anselmo</au><au>Di Mambro, Corrado</au><au>Albanese, Sonia</au><au>Ammirati, Antonio</au><au>Ravà, Lucilla</au><au>Drago, Fabrizio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Left ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5‐year follow‐up</atitle><jtitle>Pacing and clinical electrophysiology</jtitle><addtitle>Pacing Clin Electrophysiol</addtitle><date>2020-06</date><risdate>2020</risdate><volume>43</volume><issue>6</issue><spage>535</spage><epage>541</epage><pages>535-541</pages><issn>0147-8389</issn><eissn>1540-8159</eissn><abstract>Background
Small retrospective studies reported that left ventricular (LV) pacing is likely to preserve LV function in children with isolated congenital complete atrioventricular block (CCAVB). The aim of this study was to prospectively evaluate LV contractility and synchrony in a cohort of neonates/infants at pacemaker implantation and follow‐up.
Methods
Patients with CCAVB who underwent LV pacing were evaluated with electrocardiogram and echocardiogram in a single‐center, prospective study. Data were collected at implantation, at 1‐month and every year of follow‐up, up to 5 years. LV ventricular dimensions (diameters and volumes), systolic function (ejection fraction [EF] and global longitudinal strain [GLS]), and synchrony were evaluated. Data are reported as median (25th‐75th centiles).
Results
Twenty consecutive patients with CCAVB underwent pacemaker implantation (12 single‐chamber pacemaker [VVIR] and eight dual‐chamber pacemaker [DDD]) with epicardial leads: 17 on the LV apex and three on the free wall. Age at implantation was 0.3 months (1 day‐4.5 months). Patients showed good clinical status, normal LV dimensions, preserved systolic function, and synchrony at 60 (30‐60) months follow‐up. EF increased to normal values in patients with preimplantation EF <50%. Presence of antibodies and pacing mode (DDD vs VVIR) had no impact on the outcome.
Conclusions
LV pacing preserved LV systolic function and synchrony in neonates and infants with CCAVB at 5‐year follow‐up. LV EF improved in patients with low preimplantation EF. Pacing mode or the presence of autoantibodies did not demonstrated an impact on LV contractility and synchrony.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>32233121</pmid><doi>10.1111/pace.13908</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-9284-5972</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0147-8389 |
| ispartof | Pacing and clinical electrophysiology, 2020-06, Vol.43 (6), p.535-541 |
| issn | 0147-8389 1540-8159 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2385268122 |
| source | Wiley Online Library - AutoHoldings Journals |
| subjects | alternative pacing sites Autoantibodies cardiac pacing children congenital atrioventricular block Contractility Echocardiography EKG Heart Heart failure Infants Neonates Pacemakers Ventricle |
| title | Left ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5‐year follow‐up |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T03%3A19%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Left%20ventricular%20(LV)%20pacing%20in%20newborns%20and%20infants:%20Echo%20assessment%20of%20LV%20systolic%20function%20and%20synchrony%20at%205%E2%80%90year%20follow%E2%80%90up&rft.jtitle=Pacing%20and%20clinical%20electrophysiology&rft.au=Silvetti,%20Massimo%20Stefano&rft.date=2020-06&rft.volume=43&rft.issue=6&rft.spage=535&rft.epage=541&rft.pages=535-541&rft.issn=0147-8389&rft.eissn=1540-8159&rft_id=info:doi/10.1111/pace.13908&rft_dat=%3Cproquest_cross%3E2385268122%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2413270544&rft_id=info:pmid/32233121&rfr_iscdi=true |