Intracellular Generation of Superoxide by TiO2 Nanoparticles Decreases Histone Deacetylase 9 (HDAC9), an Epigenetic Modifier

Titanium dioxide (TiO2) nanoparticles are used on a massive scale in commercial and industrial products. Of specific concern is how the inhalation of these nanoparticles in a manufacturing setting may affect human health. We examine the cellular response to TiO2 nanoparticles using a combination of...

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Veröffentlicht in:	Bioconjugate chemistry 2020-05, Vol.31 (5), p.1354-1361
Hauptverfasser:	Jayaram, Dhanya T, Payne, Christine K
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalase Coronas Epigenetics Fluorescence Fluorescence microscopy Gene expression Histone deacetylase Histones Industrial products Inhalation Intracellular Nanoparticles Oxidative stress Proteins Reactive oxygen species Respiration Superoxide dismutase Titanium dioxide Western blotting
Online-Zugang:	Volltext
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