The flavonoid-enriched extract from the root of Smilax china L. inhibits inflammatory responses via the TLR-4-mediated signaling pathway

Smilax china L. has been used clinically to treat various inflammatory disorders with a long history. To investigate the mechanisms underlying anti-inflammatory action of the extract from the herb. The extract was identified and quantified using the Ultra Performance Liquid Chromatography-Photo Diod...

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Veröffentlicht in:	Journal of ethnopharmacology 2020-06, Vol.256 (NA), p.112785-112785, Article 112785
Hauptverfasser:	Feng, Haixing, He, Yanling, La, Lei, Hou, Chuqi, Song, Luyao, Yang, Qin, Wu, Fuling, Liu, Wenqin, Hou, Lianbing, Li, Yan, Wang, Chunxia, Li, Yuhao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Catalase - metabolism Cytokines - metabolism Flavonoids Flavonoids - pharmacology Glutathione - metabolism Inflammation Inflammation - drug therapy Inflammation - metabolism Inflammation Mediators - metabolism Interleukin-1beta - metabolism Male NF-kappa B - metabolism Plant Extracts - pharmacology Rats Rats, Wistar Signal Transduction - drug effects Smilax china L Superoxide Dismutase - metabolism TLR-4 Toll-Like Receptor 4 - metabolism Tumor Necrosis Factor-alpha - metabolism
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