miR-128-3p Is a Novel Regulator of Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Diseases

MicroRNAs (miRNAs, miRs) are small noncoding RNAs that modulate gene expression by negatively regulating translation of target genes. Although the role of several miRNAs in vascular smooth muscle cells (VSMCs) has been extensively characterized, the function of miRNA-128-3p (miR-128) is still unknow...

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Veröffentlicht in:	Circulation research 2020-06, Vol.126 (12), p.e120-e135
Hauptverfasser:	Farina, Floriana Maria, Hall, Ignacio Fernando, Serio, Simone, Zani, Stefania, Climent, Montserrat, Salvarani, Nicolò, Carullo, Pierluigi, Civilini, Efrem, Condorelli, Gianluigi, Elia, Leonardo, Quintavalle, Manuela
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carotid Stenosis - genetics Carotid Stenosis - metabolism Cell Differentiation Cell Movement Cell Proliferation Cells, Cultured DNA Methylation Humans Kruppel-Like Transcription Factors - genetics Kruppel-Like Transcription Factors - metabolism Mice MicroRNAs - genetics MicroRNAs - metabolism Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - physiology Myosin Heavy Chains - genetics Myosin Heavy Chains - metabolism
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