Knockdown of LINC00467 contributed to Axitinib sensitivity in hepatocellular carcinoma through miR-509-3p/PDGFRA axis

Hepatocellular carcinoma (HCC) is a common histological class of primary liver cancer with dismal prognosis. Long noncoding RNAs (lncRNAs) are increasingly documented as participators in cancers. Present study aimed to explore the role of long intergenic nonprotein-coding RNA 467 (LINC00467) in HCC....

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Veröffentlicht in:	Gene therapy 2021-11, Vol.28 (10-11), p.634-645
Hauptverfasser:	Li, Wei, He, Yufeng, Chen, Wei, Man, Wenling, Fu, Qiang, Tan, Hongtong, Guo, Huanqing, Zhou, Jingnan, Yang, Po
Format:	Artikel
Sprache:	eng
Schlagworte:	13/21 631/67/68 631/80 82/51 Apoptosis Axitinib Axitinib - therapeutic use Biomedical and Life Sciences Biomedicine Blood platelets Cancer Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology Cell Biology Cell Line, Tumor Cell Movement Cell Proliferation Cellular signal transduction Drug sensitization Drug therapy Gene Expression Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Gene Therapy Genetic aspects Health aspects Hepatocellular carcinoma Hepatoma Human Genetics Humans Liver cancer Liver Neoplasms - drug therapy Liver Neoplasms - genetics Liver Neoplasms - metabolism MicroRNAs - genetics MicroRNAs - metabolism miRNA Nanotechnology Oncology, Experimental Platelet-derived growth factor Receptor, Platelet-Derived Growth Factor alpha - genetics Receptors RNA RNA, Long Noncoding - genetics Targeted cancer therapy
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