Acute cellular rejection in small-bowel transplantation impairs NCR+ innate lymphoid cell subpopulation 3/interleukin 22 axis

Acute cellular rejection (ACR) remains as one of the main causes of graft loss and death in intestinal transplant (ITx) patients. ACR promotes intestinal injury, disruption of the mucosal barrier, bacterial translocation, and organ dysfunction. As epithelial regeneration is critical in reversing the...

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Veröffentlicht in:	Transplant immunology 2020-06, Vol.60, p.101288-101288, Article 101288
Hauptverfasser:	Pucci Molineris, Melisa, González Polo, Virginia, Rumbo, Carolina, Fuxman, Claudia, Lowestein, Carlos, Nachman, Fabio, Rumbo, Martín, Gondolesi, Gabriel, Meier, Dominik
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Acute rejection Aged Female Graft Rejection - etiology Graft Rejection - immunology Humans Immunity, Cellular Immunity, Innate Innate lymphoid cells Interleukin-22 Interleukins - metabolism Intestinal transplant Intestines - pathology Intestines - transplantation Lymphocytes - immunology Male Middle Aged Natural Cytotoxicity Triggering Receptor 1 - metabolism Organ Transplantation Signal Transduction
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