Effect of suprascapular nerve injury on rotator cuff enthesis
Numerous reports have shown that retracted rotator cuff tears may cause suprascapular nerve injury, and nerve injury causes atrophy and fat accumulation in the rotator cuff muscles. However, the effect of suprascapular nerve injury on rotator cuff enthesis has not been directly defined. This study a...
Gespeichert in:
| Veröffentlicht in: | Journal of shoulder and elbow surgery 2020-08, Vol.29 (8), p.1584-1589 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1589 |
|---|---|
| container_issue | 8 |
| container_start_page | 1584 |
| container_title | Journal of shoulder and elbow surgery |
| container_volume | 29 |
| creator | Gereli, Arel Uslu, Serap Okur, Beril Ulku, Tekin Kerem Kocaoğlu, Barış Yoo, Yon-Sik |
| description | Numerous reports have shown that retracted rotator cuff tears may cause suprascapular nerve injury, and nerve injury causes atrophy and fat accumulation in the rotator cuff muscles. However, the effect of suprascapular nerve injury on rotator cuff enthesis has not been directly defined. This study aimed to investigate the effect of suprascapular nerve injury on rotator cuff enthesis.
Twenty-four Wistar albino rats underwent bilateral transection of the suprascapular nerve. Additional 6 rats were used as the sham group. Bilateral supraspinatus and infraspinatus entheses were examined after 1, 4, 8, and 12 weeks of nerve transection. Histomorphometric analyses were performed for each zone of enthesis.
Compared with normal enthesis, significant and consistent decrease in cellularity were observed in the tendon and bone at all time points (P < .001). Collagen bundle diameter in the tendon also decreased in a similar manner (P < .001). Apart from the tendon and bone zones, fibrocartilage and calcified fibrocartilage zones showed similar response, and significant decrease in cellularity was observed 8 weeks after nerve transection (P < .001).
This study identifies suprascapular nerve injury as an underlying mechanism leading to compromise of the rotator cuff enthesis structure. Suprascapular nerve injury may be considered as an etiologic factor for the impaired healing after repair of a massive tear. |
| doi_str_mv | 10.1016/j.jse.2019.12.028 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2381847843</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1058274620300185</els_id><sourcerecordid>2381847843</sourcerecordid><originalsourceid>FETCH-LOGICAL-c419t-d9d6e1ea644f6f7798cafcb1576653febb6b0b4d9b5b1c5c6e05f41af61d5f253</originalsourceid><addsrcrecordid>eNp9kD1PwzAURS0EolD4ASwoI0uCn2M7sRADqsqHVIkFZstxnkWiNCl2Uqn_HlctjEzvDude6R1CboBmQEHet1kbMGMUVAYso6w8IRcgcpZKQelpzFSUKSu4nJHLEFpKqeKUnZNZzkCpQsgL8rh0Du2YDC4J08abYM1m6oxPevRbTJq-nfwuGfrED6MZB5_YybkE-_ELQxOuyJkzXcDr452Tz-flx-I1Xb2_vC2eVqnloMa0VrVEQCM5d9IVhSqtcbYCUUgpcodVJSta8VpVogIrrEQqHAfjJNTCMZHPyd1hd-OH7wnDqNdNsNh1psdhCprlJZS8KHkeUTig1g8heHR645u18TsNVO-t6VZHa3pvTQPT0Vrs3B7np2qN9V_jV1MEHg4Axie3DXodbIO9xbrx0Z6uh-af-R_uP33V</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2381847843</pqid></control><display><type>article</type><title>Effect of suprascapular nerve injury on rotator cuff enthesis</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Gereli, Arel ; Uslu, Serap ; Okur, Beril ; Ulku, Tekin Kerem ; Kocaoğlu, Barış ; Yoo, Yon-Sik</creator><creatorcontrib>Gereli, Arel ; Uslu, Serap ; Okur, Beril ; Ulku, Tekin Kerem ; Kocaoğlu, Barış ; Yoo, Yon-Sik</creatorcontrib><description>Numerous reports have shown that retracted rotator cuff tears may cause suprascapular nerve injury, and nerve injury causes atrophy and fat accumulation in the rotator cuff muscles. However, the effect of suprascapular nerve injury on rotator cuff enthesis has not been directly defined. This study aimed to investigate the effect of suprascapular nerve injury on rotator cuff enthesis.
Twenty-four Wistar albino rats underwent bilateral transection of the suprascapular nerve. Additional 6 rats were used as the sham group. Bilateral supraspinatus and infraspinatus entheses were examined after 1, 4, 8, and 12 weeks of nerve transection. Histomorphometric analyses were performed for each zone of enthesis.
Compared with normal enthesis, significant and consistent decrease in cellularity were observed in the tendon and bone at all time points (P < .001). Collagen bundle diameter in the tendon also decreased in a similar manner (P < .001). Apart from the tendon and bone zones, fibrocartilage and calcified fibrocartilage zones showed similar response, and significant decrease in cellularity was observed 8 weeks after nerve transection (P < .001).
This study identifies suprascapular nerve injury as an underlying mechanism leading to compromise of the rotator cuff enthesis structure. Suprascapular nerve injury may be considered as an etiologic factor for the impaired healing after repair of a massive tear.</description><identifier>ISSN: 1058-2746</identifier><identifier>EISSN: 1532-6500</identifier><identifier>DOI: 10.1016/j.jse.2019.12.028</identifier><identifier>PMID: 32199756</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Collagen - ultrastructure ; Disease Models, Animal ; enthesis ; Fibrocartilage - pathology ; histomorphometry ; injury ; Male ; Peripheral Nerve Injuries - complications ; Rats ; Rats, Wistar ; Rotator cuff ; Rotator Cuff - innervation ; Rotator Cuff - pathology ; Rotator Cuff Injuries - pathology ; shoulder ; suprascapular nerve</subject><ispartof>Journal of shoulder and elbow surgery, 2020-08, Vol.29 (8), p.1584-1589</ispartof><rights>2020 Journal of Shoulder and Elbow Surgery Board of Trustees</rights><rights>Copyright © 2020 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-d9d6e1ea644f6f7798cafcb1576653febb6b0b4d9b5b1c5c6e05f41af61d5f253</citedby><cites>FETCH-LOGICAL-c419t-d9d6e1ea644f6f7798cafcb1576653febb6b0b4d9b5b1c5c6e05f41af61d5f253</cites><orcidid>0000-0002-4414-6701</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jse.2019.12.028$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32199756$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gereli, Arel</creatorcontrib><creatorcontrib>Uslu, Serap</creatorcontrib><creatorcontrib>Okur, Beril</creatorcontrib><creatorcontrib>Ulku, Tekin Kerem</creatorcontrib><creatorcontrib>Kocaoğlu, Barış</creatorcontrib><creatorcontrib>Yoo, Yon-Sik</creatorcontrib><title>Effect of suprascapular nerve injury on rotator cuff enthesis</title><title>Journal of shoulder and elbow surgery</title><addtitle>J Shoulder Elbow Surg</addtitle><description>Numerous reports have shown that retracted rotator cuff tears may cause suprascapular nerve injury, and nerve injury causes atrophy and fat accumulation in the rotator cuff muscles. However, the effect of suprascapular nerve injury on rotator cuff enthesis has not been directly defined. This study aimed to investigate the effect of suprascapular nerve injury on rotator cuff enthesis.
Twenty-four Wistar albino rats underwent bilateral transection of the suprascapular nerve. Additional 6 rats were used as the sham group. Bilateral supraspinatus and infraspinatus entheses were examined after 1, 4, 8, and 12 weeks of nerve transection. Histomorphometric analyses were performed for each zone of enthesis.
Compared with normal enthesis, significant and consistent decrease in cellularity were observed in the tendon and bone at all time points (P < .001). Collagen bundle diameter in the tendon also decreased in a similar manner (P < .001). Apart from the tendon and bone zones, fibrocartilage and calcified fibrocartilage zones showed similar response, and significant decrease in cellularity was observed 8 weeks after nerve transection (P < .001).
This study identifies suprascapular nerve injury as an underlying mechanism leading to compromise of the rotator cuff enthesis structure. Suprascapular nerve injury may be considered as an etiologic factor for the impaired healing after repair of a massive tear.</description><subject>Animals</subject><subject>Collagen - ultrastructure</subject><subject>Disease Models, Animal</subject><subject>enthesis</subject><subject>Fibrocartilage - pathology</subject><subject>histomorphometry</subject><subject>injury</subject><subject>Male</subject><subject>Peripheral Nerve Injuries - complications</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Rotator cuff</subject><subject>Rotator Cuff - innervation</subject><subject>Rotator Cuff - pathology</subject><subject>Rotator Cuff Injuries - pathology</subject><subject>shoulder</subject><subject>suprascapular nerve</subject><issn>1058-2746</issn><issn>1532-6500</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAURS0EolD4ASwoI0uCn2M7sRADqsqHVIkFZstxnkWiNCl2Uqn_HlctjEzvDude6R1CboBmQEHet1kbMGMUVAYso6w8IRcgcpZKQelpzFSUKSu4nJHLEFpKqeKUnZNZzkCpQsgL8rh0Du2YDC4J08abYM1m6oxPevRbTJq-nfwuGfrED6MZB5_YybkE-_ELQxOuyJkzXcDr452Tz-flx-I1Xb2_vC2eVqnloMa0VrVEQCM5d9IVhSqtcbYCUUgpcodVJSta8VpVogIrrEQqHAfjJNTCMZHPyd1hd-OH7wnDqNdNsNh1psdhCprlJZS8KHkeUTig1g8heHR645u18TsNVO-t6VZHa3pvTQPT0Vrs3B7np2qN9V_jV1MEHg4Axie3DXodbIO9xbrx0Z6uh-af-R_uP33V</recordid><startdate>202008</startdate><enddate>202008</enddate><creator>Gereli, Arel</creator><creator>Uslu, Serap</creator><creator>Okur, Beril</creator><creator>Ulku, Tekin Kerem</creator><creator>Kocaoğlu, Barış</creator><creator>Yoo, Yon-Sik</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4414-6701</orcidid></search><sort><creationdate>202008</creationdate><title>Effect of suprascapular nerve injury on rotator cuff enthesis</title><author>Gereli, Arel ; Uslu, Serap ; Okur, Beril ; Ulku, Tekin Kerem ; Kocaoğlu, Barış ; Yoo, Yon-Sik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-d9d6e1ea644f6f7798cafcb1576653febb6b0b4d9b5b1c5c6e05f41af61d5f253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Animals</topic><topic>Collagen - ultrastructure</topic><topic>Disease Models, Animal</topic><topic>enthesis</topic><topic>Fibrocartilage - pathology</topic><topic>histomorphometry</topic><topic>injury</topic><topic>Male</topic><topic>Peripheral Nerve Injuries - complications</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Rotator cuff</topic><topic>Rotator Cuff - innervation</topic><topic>Rotator Cuff - pathology</topic><topic>Rotator Cuff Injuries - pathology</topic><topic>shoulder</topic><topic>suprascapular nerve</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gereli, Arel</creatorcontrib><creatorcontrib>Uslu, Serap</creatorcontrib><creatorcontrib>Okur, Beril</creatorcontrib><creatorcontrib>Ulku, Tekin Kerem</creatorcontrib><creatorcontrib>Kocaoğlu, Barış</creatorcontrib><creatorcontrib>Yoo, Yon-Sik</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of shoulder and elbow surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gereli, Arel</au><au>Uslu, Serap</au><au>Okur, Beril</au><au>Ulku, Tekin Kerem</au><au>Kocaoğlu, Barış</au><au>Yoo, Yon-Sik</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of suprascapular nerve injury on rotator cuff enthesis</atitle><jtitle>Journal of shoulder and elbow surgery</jtitle><addtitle>J Shoulder Elbow Surg</addtitle><date>2020-08</date><risdate>2020</risdate><volume>29</volume><issue>8</issue><spage>1584</spage><epage>1589</epage><pages>1584-1589</pages><issn>1058-2746</issn><eissn>1532-6500</eissn><abstract>Numerous reports have shown that retracted rotator cuff tears may cause suprascapular nerve injury, and nerve injury causes atrophy and fat accumulation in the rotator cuff muscles. However, the effect of suprascapular nerve injury on rotator cuff enthesis has not been directly defined. This study aimed to investigate the effect of suprascapular nerve injury on rotator cuff enthesis.
Twenty-four Wistar albino rats underwent bilateral transection of the suprascapular nerve. Additional 6 rats were used as the sham group. Bilateral supraspinatus and infraspinatus entheses were examined after 1, 4, 8, and 12 weeks of nerve transection. Histomorphometric analyses were performed for each zone of enthesis.
Compared with normal enthesis, significant and consistent decrease in cellularity were observed in the tendon and bone at all time points (P < .001). Collagen bundle diameter in the tendon also decreased in a similar manner (P < .001). Apart from the tendon and bone zones, fibrocartilage and calcified fibrocartilage zones showed similar response, and significant decrease in cellularity was observed 8 weeks after nerve transection (P < .001).
This study identifies suprascapular nerve injury as an underlying mechanism leading to compromise of the rotator cuff enthesis structure. Suprascapular nerve injury may be considered as an etiologic factor for the impaired healing after repair of a massive tear.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>32199756</pmid><doi>10.1016/j.jse.2019.12.028</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-4414-6701</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1058-2746 |
| ispartof | Journal of shoulder and elbow surgery, 2020-08, Vol.29 (8), p.1584-1589 |
| issn | 1058-2746 1532-6500 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2381847843 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Collagen - ultrastructure Disease Models, Animal enthesis Fibrocartilage - pathology histomorphometry injury Male Peripheral Nerve Injuries - complications Rats Rats, Wistar Rotator cuff Rotator Cuff - innervation Rotator Cuff - pathology Rotator Cuff Injuries - pathology shoulder suprascapular nerve |
| title | Effect of suprascapular nerve injury on rotator cuff enthesis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T06%3A27%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20suprascapular%20nerve%20injury%20on%20rotator%20cuff%20enthesis&rft.jtitle=Journal%20of%20shoulder%20and%20elbow%20surgery&rft.au=Gereli,%20Arel&rft.date=2020-08&rft.volume=29&rft.issue=8&rft.spage=1584&rft.epage=1589&rft.pages=1584-1589&rft.issn=1058-2746&rft.eissn=1532-6500&rft_id=info:doi/10.1016/j.jse.2019.12.028&rft_dat=%3Cproquest_cross%3E2381847843%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2381847843&rft_id=info:pmid/32199756&rft_els_id=S1058274620300185&rfr_iscdi=true |