Stimuli-Responsive Actuator Fabricated by Dynamic Asymmetric Femtosecond Bessel Beam for In Situ Particle and Cell Manipulation

Microscale intelligent actuators capable of sensitive and accurate manipulation under external stimuli hold great promise in various fields including precision sensors and biomedical devices. Current microactuators, however, are often limited to a multiple-step fabrication process and multimaterials...

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Veröffentlicht in:ACS nano 2020-05, Vol.14 (5), p.5233-5242
Hauptverfasser: Li, Rui, Jin, Dongdong, Pan, Deng, Ji, Shengyun, Xin, Chen, Liu, Guangli, Fan, Shengying, Wu, Hao, Li, Jiawen, Hu, Yanlei, Wu, Dong, Zhang, Li, Chu, Jiaru
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container_issue 5
container_start_page 5233
container_title ACS nano
container_volume 14
creator Li, Rui
Jin, Dongdong
Pan, Deng
Ji, Shengyun
Xin, Chen
Liu, Guangli
Fan, Shengying
Wu, Hao
Li, Jiawen
Hu, Yanlei
Wu, Dong
Zhang, Li
Chu, Jiaru
description Microscale intelligent actuators capable of sensitive and accurate manipulation under external stimuli hold great promise in various fields including precision sensors and biomedical devices. Current microactuators, however, are often limited to a multiple-step fabrication process and multimaterials. Here, a pH-triggered soft microactuator (
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Current microactuators, however, are often limited to a multiple-step fabrication process and multimaterials. Here, a pH-triggered soft microactuator (&lt;100 μm) with simple structure, one-step fabrication process, and single material is proposed, which is composed of deformable hydrogel microstructures fabricated by an asymmetric femtosecond Bessel beam. To further explore the swelling–shrinking mechanism, the hydrogel porosity difference between expansion and contraction states is investigated. In addition, by introducing the dynamic holographic processing and splicing processing method, more complex responsive microstructures (S-shaped, C-shaped, and tortile chiral structures) are rapidly fabricated, which exhibit tremendous expected deformation characteristics. Finally, as a proof of concept, a pH-responsive microgripper is fabricated for in situ capturing polystyrene (PS) particles and neural stem cells rapidly. 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title Stimuli-Responsive Actuator Fabricated by Dynamic Asymmetric Femtosecond Bessel Beam for In Situ Particle and Cell Manipulation
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