Rapid fabrication of collagen bundles mimicking tumor-associated collagen architectures

Stromal collagen is upregulated surrounding a solid tumor and presents as dense, thick, linearized, and aligned bundles. The collagen bundles are continually remodeled during tumor progression, and their orientation with respect to the tumor boundary has been correlated with invasive state. Currentl...

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Veröffentlicht in:Acta biomaterialia 2020-05, Vol.108, p.128-141
Hauptverfasser: Gong, Xiangyu, Kulwatno, Jonathan, Mills, K.L.
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Sprache:eng
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