C−H Amination via Nitrene Transfer Catalyzed by Mononuclear Non‐Heme Iron‐Dependent Enzymes

Expanding the reaction scope of natural metalloenzymes can provide new opportunities for biocatalysis. Mononuclear non‐heme iron‐dependent enzymes represent a large class of biological catalysts involved in the biosynthesis of natural products and catabolism of xenobiotics, among other processes. He...

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Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2020-07, Vol.21 (14), p.1981-1987
Hauptverfasser:	Vila, Maria Agustina, Steck, Viktoria, Rodriguez Giordano, Sonia, Carrera, Ignacio, Fasan, Rudi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amination Biocatalysts Bioreactors Biosynthesis Catabolism Catalysis Catalysts C−H amination Enzymes Heme Iron Ketoglutaric acid Naphthalene Natural products nitrene transfer non-heme iron-dependent oxidases protein engineering Rieske diooxygenases Substrates Xenobiotics
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