Distribution and Cytokine Profile of Peripheral B Cell Subsets Is Perturbed in Pediatric IBD and Partially Restored During a Successful IFX Therapy

Abstract Background The role of B cells in inflammatory bowel disease (IBD) is ambiguous, as B cells may have both pathogenic and protective functions in IBD. We studied B cell subsets before and after initiation of an anti-tumor necrosis factor alpha (anti-TNFα) therapy in pediatric IBD. The aim of...

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Veröffentlicht in:Inflammatory bowel diseases 2021-02, Vol.27 (2), p.224-235
Hauptverfasser: Schnell, Alexander, Schwarz, Benedikt, Wahlbuhl, Mandy, Allabauer, Ida, Hess, Merlin, Weber, Sabine, Werner, Felix, Schmidt, Hannah, Rechenauer, Tobias, Siebenlist, Gregor, Kaspar, Sonja, Ehrsam, Christoph, Rieger, Daniel, Rückel, Aline, Metzler, Markus, Christoph, Jan, Woelfle, Joachim, Rascher, Wolfgang, Hoerning, André
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Sprache:eng
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