Calcium Dialkylamine Diazeniumdiolates: Synthesis, Stability, and Nitric Oxide Generation
The therapeutic application of nitric oxide, an endogenous cellular signaling molecule, has been limited due to the difficulty of developing stable pro-drugs with slow kinetics of NO release. Diazeniumdiolates are valuable NO donors; however, synthetic challenges have hampered their use. O2-alkylati...
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Veröffentlicht in: | Journal of organic chemistry 2020-04, Vol.85 (7), p.4807-4812 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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