Endovascular thrombectomy for tandem acute ischemic stroke associated with cervical artery dissection: a systematic review and meta-analysis

Purpose Strokes associated with cervical artery dissection have been managed primarily with antithrombotics with poor outcomes. The additive role of endovascular thrombectomy remains unclear. The objective was to perform systematic review and meta-analysis to compare endovascular thrombectomy and me...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neuroradiology 2020-07, Vol.62 (7), p.861-866
Hauptverfasser: Dmytriw, Adam A., Phan, Kevin, Maingard, Julian, Mobbs, Ralph J., Brooks, Mark, Chen, Karen, Yang, Victor, Kok, Hong Kuan, Hirsch, Joshua A., Barras, Christen D., Chandra, Ronil V., Asadi, Hamed
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 866
container_issue 7
container_start_page 861
container_title Neuroradiology
container_volume 62
creator Dmytriw, Adam A.
Phan, Kevin
Maingard, Julian
Mobbs, Ralph J.
Brooks, Mark
Chen, Karen
Yang, Victor
Kok, Hong Kuan
Hirsch, Joshua A.
Barras, Christen D.
Chandra, Ronil V.
Asadi, Hamed
description Purpose Strokes associated with cervical artery dissection have been managed primarily with antithrombotics with poor outcomes. The additive role of endovascular thrombectomy remains unclear. The objective was to perform systematic review and meta-analysis to compare endovascular thrombectomy and medical therapy for acute ischemic stroke associated with cervical artery dissection. Methods Studies from six electronic databases included outcomes of patient cohorts with acute ischemic stroke secondary to cervical artery dissection who underwent treatment with endovascular thrombectomy. A meta-analysis of proportions was conducted with a random effects model. Modified Rankin score at 90 days (mRS 0–2) was the primary outcome. Other outcomes included proportion of patients with thrombolysis in cerebral infarction (TICI) 2b-3 flow, 90-day mortality rate, and 90-day symptomatic intracerebral hemorrhage (sICH) rate. Results Six studies were included, comprising 193 cases that underwent thrombectomy compared with 59 cases that were managed medically. Successful recanalization with a pooled proportion of thrombolysis in cerebral infarction (TICI) 2b-3 flow in the thrombectomy group was 74%. Favorable outcome (mRS 0–2) was superior in the pooled thrombectomy group (62.9%, 95% CI 55.8–69.5%) compared with medical management (41.5%, 95% CI 29.0–55.1%, P  = 0.006). The pooled rate of 90-day mortality was similar for endovascular vs medical (8.6% vs 6.3%). The pooled rate of symptomatic intracranial haemorrhage (sICH) did not significantly differ (5.9% vs 4.2%, P  = 0.60). Conclusions Current data suggest that endovascular thrombectomy may be an option in patients with acute ischemic stroke due to cervical artery dissection. This requires further confirmation in higher quality prospective studies.
doi_str_mv 10.1007/s00234-020-02388-x
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2377337238</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2377337238</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-de0c7add792e4a6e72d7cfc88614f90e4abdcffe658873ddcec09eb4088007e63</originalsourceid><addsrcrecordid>eNp9kcFu1DAQhi0EotvCC3BAlrhwCYztbOxwQ1WhSJW4wNny2hPWJYmLx9k278BDY9gCEgcOlqWZ7__Hnp-xZwJeCQD9mgCkahuQUI8yprl7wDaiVbIRvYSHbFP7plF9CyfslOgaAJRW-jE7UVJ0XdvqDft-MYd0cOSX0WVe9jlNO_QlTSsfUi24OeDEnV8K8kh-j1P0nEpOX5E7ouSjKxj4bSx77jEfoncjd7lgXnmIRNUrpvkNd5xWKji5UvUZDxFvefXmExbXuNmNK0V6wh4NbiR8en-fsc_vLj6dXzZXH99_OH971Xilt6UJCF67EHQvsXUdahm0H7wxnWiHHmptF_wwYLc1RqsQPHrocdeCMXVt2Kkz9vLoe5PTtwWp2Kn-DcfRzZgWslJprZSuO63oi3_Q67Tk-t5KtaIDZUBsKyWPlM-JKONgb3KcXF6tAPszK3vMytas7K-s7F0VPb-3XnYThj-S3-FUQB0Bqq35C-a_s_9j-wNV46PC</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2416038015</pqid></control><display><type>article</type><title>Endovascular thrombectomy for tandem acute ischemic stroke associated with cervical artery dissection: a systematic review and meta-analysis</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Dmytriw, Adam A. ; Phan, Kevin ; Maingard, Julian ; Mobbs, Ralph J. ; Brooks, Mark ; Chen, Karen ; Yang, Victor ; Kok, Hong Kuan ; Hirsch, Joshua A. ; Barras, Christen D. ; Chandra, Ronil V. ; Asadi, Hamed</creator><creatorcontrib>Dmytriw, Adam A. ; Phan, Kevin ; Maingard, Julian ; Mobbs, Ralph J. ; Brooks, Mark ; Chen, Karen ; Yang, Victor ; Kok, Hong Kuan ; Hirsch, Joshua A. ; Barras, Christen D. ; Chandra, Ronil V. ; Asadi, Hamed</creatorcontrib><description>Purpose Strokes associated with cervical artery dissection have been managed primarily with antithrombotics with poor outcomes. The additive role of endovascular thrombectomy remains unclear. The objective was to perform systematic review and meta-analysis to compare endovascular thrombectomy and medical therapy for acute ischemic stroke associated with cervical artery dissection. Methods Studies from six electronic databases included outcomes of patient cohorts with acute ischemic stroke secondary to cervical artery dissection who underwent treatment with endovascular thrombectomy. A meta-analysis of proportions was conducted with a random effects model. Modified Rankin score at 90 days (mRS 0–2) was the primary outcome. Other outcomes included proportion of patients with thrombolysis in cerebral infarction (TICI) 2b-3 flow, 90-day mortality rate, and 90-day symptomatic intracerebral hemorrhage (sICH) rate. Results Six studies were included, comprising 193 cases that underwent thrombectomy compared with 59 cases that were managed medically. Successful recanalization with a pooled proportion of thrombolysis in cerebral infarction (TICI) 2b-3 flow in the thrombectomy group was 74%. Favorable outcome (mRS 0–2) was superior in the pooled thrombectomy group (62.9%, 95% CI 55.8–69.5%) compared with medical management (41.5%, 95% CI 29.0–55.1%, P  = 0.006). The pooled rate of 90-day mortality was similar for endovascular vs medical (8.6% vs 6.3%). The pooled rate of symptomatic intracranial haemorrhage (sICH) did not significantly differ (5.9% vs 4.2%, P  = 0.60). Conclusions Current data suggest that endovascular thrombectomy may be an option in patients with acute ischemic stroke due to cervical artery dissection. This requires further confirmation in higher quality prospective studies.</description><identifier>ISSN: 0028-3940</identifier><identifier>EISSN: 1432-1920</identifier><identifier>DOI: 10.1007/s00234-020-02388-x</identifier><identifier>PMID: 32166447</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Aneurysm, Dissecting - complications ; Aneurysm, Dissecting - surgery ; Cardiovascular system ; Cerebral infarction ; Dissection ; Hemorrhage ; Humans ; Imaging ; Infarction ; Interventional Neuroradiology ; Intracranial Aneurysm - complications ; Intracranial Aneurysm - surgery ; Ischemia ; Ischemic Stroke - etiology ; Ischemic Stroke - surgery ; Medicine ; Medicine &amp; Public Health ; Meta-analysis ; Mortality ; Neurology ; Neuroradiology ; Neurosciences ; Neurosurgery ; Patients ; Radiology ; Stroke ; Systematic review ; Thrombectomy ; Thrombolysis</subject><ispartof>Neuroradiology, 2020-07, Vol.62 (7), p.861-866</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020</rights><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-de0c7add792e4a6e72d7cfc88614f90e4abdcffe658873ddcec09eb4088007e63</citedby><cites>FETCH-LOGICAL-c375t-de0c7add792e4a6e72d7cfc88614f90e4abdcffe658873ddcec09eb4088007e63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00234-020-02388-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00234-020-02388-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32166447$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dmytriw, Adam A.</creatorcontrib><creatorcontrib>Phan, Kevin</creatorcontrib><creatorcontrib>Maingard, Julian</creatorcontrib><creatorcontrib>Mobbs, Ralph J.</creatorcontrib><creatorcontrib>Brooks, Mark</creatorcontrib><creatorcontrib>Chen, Karen</creatorcontrib><creatorcontrib>Yang, Victor</creatorcontrib><creatorcontrib>Kok, Hong Kuan</creatorcontrib><creatorcontrib>Hirsch, Joshua A.</creatorcontrib><creatorcontrib>Barras, Christen D.</creatorcontrib><creatorcontrib>Chandra, Ronil V.</creatorcontrib><creatorcontrib>Asadi, Hamed</creatorcontrib><title>Endovascular thrombectomy for tandem acute ischemic stroke associated with cervical artery dissection: a systematic review and meta-analysis</title><title>Neuroradiology</title><addtitle>Neuroradiology</addtitle><addtitle>Neuroradiology</addtitle><description>Purpose Strokes associated with cervical artery dissection have been managed primarily with antithrombotics with poor outcomes. The additive role of endovascular thrombectomy remains unclear. The objective was to perform systematic review and meta-analysis to compare endovascular thrombectomy and medical therapy for acute ischemic stroke associated with cervical artery dissection. Methods Studies from six electronic databases included outcomes of patient cohorts with acute ischemic stroke secondary to cervical artery dissection who underwent treatment with endovascular thrombectomy. A meta-analysis of proportions was conducted with a random effects model. Modified Rankin score at 90 days (mRS 0–2) was the primary outcome. Other outcomes included proportion of patients with thrombolysis in cerebral infarction (TICI) 2b-3 flow, 90-day mortality rate, and 90-day symptomatic intracerebral hemorrhage (sICH) rate. Results Six studies were included, comprising 193 cases that underwent thrombectomy compared with 59 cases that were managed medically. Successful recanalization with a pooled proportion of thrombolysis in cerebral infarction (TICI) 2b-3 flow in the thrombectomy group was 74%. Favorable outcome (mRS 0–2) was superior in the pooled thrombectomy group (62.9%, 95% CI 55.8–69.5%) compared with medical management (41.5%, 95% CI 29.0–55.1%, P  = 0.006). The pooled rate of 90-day mortality was similar for endovascular vs medical (8.6% vs 6.3%). The pooled rate of symptomatic intracranial haemorrhage (sICH) did not significantly differ (5.9% vs 4.2%, P  = 0.60). Conclusions Current data suggest that endovascular thrombectomy may be an option in patients with acute ischemic stroke due to cervical artery dissection. This requires further confirmation in higher quality prospective studies.</description><subject>Aneurysm, Dissecting - complications</subject><subject>Aneurysm, Dissecting - surgery</subject><subject>Cardiovascular system</subject><subject>Cerebral infarction</subject><subject>Dissection</subject><subject>Hemorrhage</subject><subject>Humans</subject><subject>Imaging</subject><subject>Infarction</subject><subject>Interventional Neuroradiology</subject><subject>Intracranial Aneurysm - complications</subject><subject>Intracranial Aneurysm - surgery</subject><subject>Ischemia</subject><subject>Ischemic Stroke - etiology</subject><subject>Ischemic Stroke - surgery</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Meta-analysis</subject><subject>Mortality</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Patients</subject><subject>Radiology</subject><subject>Stroke</subject><subject>Systematic review</subject><subject>Thrombectomy</subject><subject>Thrombolysis</subject><issn>0028-3940</issn><issn>1432-1920</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kcFu1DAQhi0EotvCC3BAlrhwCYztbOxwQ1WhSJW4wNny2hPWJYmLx9k278BDY9gCEgcOlqWZ7__Hnp-xZwJeCQD9mgCkahuQUI8yprl7wDaiVbIRvYSHbFP7plF9CyfslOgaAJRW-jE7UVJ0XdvqDft-MYd0cOSX0WVe9jlNO_QlTSsfUi24OeDEnV8K8kh-j1P0nEpOX5E7ouSjKxj4bSx77jEfoncjd7lgXnmIRNUrpvkNd5xWKji5UvUZDxFvefXmExbXuNmNK0V6wh4NbiR8en-fsc_vLj6dXzZXH99_OH971Xilt6UJCF67EHQvsXUdahm0H7wxnWiHHmptF_wwYLc1RqsQPHrocdeCMXVt2Kkz9vLoe5PTtwWp2Kn-DcfRzZgWslJprZSuO63oi3_Q67Tk-t5KtaIDZUBsKyWPlM-JKONgb3KcXF6tAPszK3vMytas7K-s7F0VPb-3XnYThj-S3-FUQB0Bqq35C-a_s_9j-wNV46PC</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>Dmytriw, Adam A.</creator><creator>Phan, Kevin</creator><creator>Maingard, Julian</creator><creator>Mobbs, Ralph J.</creator><creator>Brooks, Mark</creator><creator>Chen, Karen</creator><creator>Yang, Victor</creator><creator>Kok, Hong Kuan</creator><creator>Hirsch, Joshua A.</creator><creator>Barras, Christen D.</creator><creator>Chandra, Ronil V.</creator><creator>Asadi, Hamed</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20200701</creationdate><title>Endovascular thrombectomy for tandem acute ischemic stroke associated with cervical artery dissection: a systematic review and meta-analysis</title><author>Dmytriw, Adam A. ; Phan, Kevin ; Maingard, Julian ; Mobbs, Ralph J. ; Brooks, Mark ; Chen, Karen ; Yang, Victor ; Kok, Hong Kuan ; Hirsch, Joshua A. ; Barras, Christen D. ; Chandra, Ronil V. ; Asadi, Hamed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-de0c7add792e4a6e72d7cfc88614f90e4abdcffe658873ddcec09eb4088007e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aneurysm, Dissecting - complications</topic><topic>Aneurysm, Dissecting - surgery</topic><topic>Cardiovascular system</topic><topic>Cerebral infarction</topic><topic>Dissection</topic><topic>Hemorrhage</topic><topic>Humans</topic><topic>Imaging</topic><topic>Infarction</topic><topic>Interventional Neuroradiology</topic><topic>Intracranial Aneurysm - complications</topic><topic>Intracranial Aneurysm - surgery</topic><topic>Ischemia</topic><topic>Ischemic Stroke - etiology</topic><topic>Ischemic Stroke - surgery</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Meta-analysis</topic><topic>Mortality</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Patients</topic><topic>Radiology</topic><topic>Stroke</topic><topic>Systematic review</topic><topic>Thrombectomy</topic><topic>Thrombolysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dmytriw, Adam A.</creatorcontrib><creatorcontrib>Phan, Kevin</creatorcontrib><creatorcontrib>Maingard, Julian</creatorcontrib><creatorcontrib>Mobbs, Ralph J.</creatorcontrib><creatorcontrib>Brooks, Mark</creatorcontrib><creatorcontrib>Chen, Karen</creatorcontrib><creatorcontrib>Yang, Victor</creatorcontrib><creatorcontrib>Kok, Hong Kuan</creatorcontrib><creatorcontrib>Hirsch, Joshua A.</creatorcontrib><creatorcontrib>Barras, Christen D.</creatorcontrib><creatorcontrib>Chandra, Ronil V.</creatorcontrib><creatorcontrib>Asadi, Hamed</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Advanced Technologies &amp; Aerospace Database</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroradiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dmytriw, Adam A.</au><au>Phan, Kevin</au><au>Maingard, Julian</au><au>Mobbs, Ralph J.</au><au>Brooks, Mark</au><au>Chen, Karen</au><au>Yang, Victor</au><au>Kok, Hong Kuan</au><au>Hirsch, Joshua A.</au><au>Barras, Christen D.</au><au>Chandra, Ronil V.</au><au>Asadi, Hamed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endovascular thrombectomy for tandem acute ischemic stroke associated with cervical artery dissection: a systematic review and meta-analysis</atitle><jtitle>Neuroradiology</jtitle><stitle>Neuroradiology</stitle><addtitle>Neuroradiology</addtitle><date>2020-07-01</date><risdate>2020</risdate><volume>62</volume><issue>7</issue><spage>861</spage><epage>866</epage><pages>861-866</pages><issn>0028-3940</issn><eissn>1432-1920</eissn><abstract>Purpose Strokes associated with cervical artery dissection have been managed primarily with antithrombotics with poor outcomes. The additive role of endovascular thrombectomy remains unclear. The objective was to perform systematic review and meta-analysis to compare endovascular thrombectomy and medical therapy for acute ischemic stroke associated with cervical artery dissection. Methods Studies from six electronic databases included outcomes of patient cohorts with acute ischemic stroke secondary to cervical artery dissection who underwent treatment with endovascular thrombectomy. A meta-analysis of proportions was conducted with a random effects model. Modified Rankin score at 90 days (mRS 0–2) was the primary outcome. Other outcomes included proportion of patients with thrombolysis in cerebral infarction (TICI) 2b-3 flow, 90-day mortality rate, and 90-day symptomatic intracerebral hemorrhage (sICH) rate. Results Six studies were included, comprising 193 cases that underwent thrombectomy compared with 59 cases that were managed medically. Successful recanalization with a pooled proportion of thrombolysis in cerebral infarction (TICI) 2b-3 flow in the thrombectomy group was 74%. Favorable outcome (mRS 0–2) was superior in the pooled thrombectomy group (62.9%, 95% CI 55.8–69.5%) compared with medical management (41.5%, 95% CI 29.0–55.1%, P  = 0.006). The pooled rate of 90-day mortality was similar for endovascular vs medical (8.6% vs 6.3%). The pooled rate of symptomatic intracranial haemorrhage (sICH) did not significantly differ (5.9% vs 4.2%, P  = 0.60). Conclusions Current data suggest that endovascular thrombectomy may be an option in patients with acute ischemic stroke due to cervical artery dissection. This requires further confirmation in higher quality prospective studies.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32166447</pmid><doi>10.1007/s00234-020-02388-x</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0028-3940
ispartof Neuroradiology, 2020-07, Vol.62 (7), p.861-866
issn 0028-3940
1432-1920
language eng
recordid cdi_proquest_miscellaneous_2377337238
source MEDLINE; Springer Nature - Complete Springer Journals
subjects Aneurysm, Dissecting - complications
Aneurysm, Dissecting - surgery
Cardiovascular system
Cerebral infarction
Dissection
Hemorrhage
Humans
Imaging
Infarction
Interventional Neuroradiology
Intracranial Aneurysm - complications
Intracranial Aneurysm - surgery
Ischemia
Ischemic Stroke - etiology
Ischemic Stroke - surgery
Medicine
Medicine & Public Health
Meta-analysis
Mortality
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Patients
Radiology
Stroke
Systematic review
Thrombectomy
Thrombolysis
title Endovascular thrombectomy for tandem acute ischemic stroke associated with cervical artery dissection: a systematic review and meta-analysis
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T05%3A31%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Endovascular%20thrombectomy%20for%20tandem%20acute%20ischemic%20stroke%20associated%20with%20cervical%20artery%20dissection:%20a%20systematic%20review%20and%20meta-analysis&rft.jtitle=Neuroradiology&rft.au=Dmytriw,%20Adam%20A.&rft.date=2020-07-01&rft.volume=62&rft.issue=7&rft.spage=861&rft.epage=866&rft.pages=861-866&rft.issn=0028-3940&rft.eissn=1432-1920&rft_id=info:doi/10.1007/s00234-020-02388-x&rft_dat=%3Cproquest_cross%3E2377337238%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2416038015&rft_id=info:pmid/32166447&rfr_iscdi=true