Preparation, characterization, and sonodynamic antitumor effect of the folate receptor targeted FA‐EN‐β‐CD containing hematoporphyrin in vitro

To improve water solubility, reduce phototoxicity and increase the tumor‐targeting ability of hematoporphyrin (Hp) as a sonosensitizer for sonodynamic therapy under ultrasonic conditions, a novel folate receptor (FR)‐targeted, folate‐conjugated ethylenediamine‐β‐cyclodextrin (FA‐EN‐β‐CD) containing...

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Veröffentlicht in:	Drug development research 2020-08, Vol.81 (5), p.585-592
Hauptverfasser:	Wang, Chuanjin, Du, Fuqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antitumor activity Cyclodextrins Drug delivery Drug delivery systems Ethylenediamine folate‐conjugated ethylenediamine‐β‐cyclodextrin Folic acid Growth inhibition hematoporphyrin Phototoxicity Receptors sonodynamic antitumor in vitro Ultrasound Vitamin B β-Cyclodextrin
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