Identification of TIE2 as a susceptibility gene for neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

PurposeThe endothelial and cell-specific angiopoietin-Tie pathway plays an important regulatory role in angiogenesis. In this study, we investigated the associations of the TIE2 (tyrosine kinase, endothelial, TEK) gene with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal...

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Veröffentlicht in:	British journal of ophthalmology 2021-07, Vol.105 (7), p.1035-1040
Hauptverfasser:	Chen, Zhen Ji, Ma, Li, Brelen, Marten E, Chen, Haoyu, Tsujikawa, Motokazu, Lai, Timothy Y, Ho, Mary, Sayanagi, Kaori, Hara, Chikako, Hashida, Noriyasu, Tam, Pancy OS, Young, Alvin L, Nishida, Kohji, Tham, Clement C, Pang, Chi Pui, Chen, Li Jia
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Angiogenesis Asian people Disease Gender Genes Genomes Haplotypes Ligands Macular degeneration Medical imaging
Online-Zugang:	Volltext
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