Generation and characterization of dipeptidyl peptidase-IV inhibitory peptides from trypsin-hydrolyzed α-lactalbumin-rich whey proteins

•The novel DPP-IV inhibitory peptide LDQWLCEKL from α-lactalbumin was identified.•CCD and RSM were used to screen the optimal combination of hydrolysis conditions.•The IC50 of hydrolysate against DPP-IV under the optimal conditions is 0.409 μM.•The IC50 of the LDQWLCEKL derived from α-lactalbumin wa...

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Veröffentlicht in:	Food chemistry 2020-07, Vol.318, p.126333-126333, Article 126333
Hauptverfasser:	Jia, Cheng-li, Hussain, Naveed, Joy Ujiroghene, Obaroakpo, Pang, Xiao-yang, Zhang, Shu-wen, Lu, Jing, Liu, Lu, Lv, Jia-ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioactive peptides Dipeptidyl peptidase-IV (DPP-IV) Mode of inhibition Response surface methodology α-Lactalbumin
Online-Zugang:	Volltext
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