The effect of second-generation cryoablation without electrical mapping in persistent AF using continuous monitoring

Background Second-generation cryoballoon ablation is safe and effective in patients with persistent atrial fibrillation (AF). The aim of this study is to report the real long-term AF burden and freedom from AF post-cryoablation using continuous monitoring, and to assess whether intraoperative confir...

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Veröffentlicht in:Journal of interventional cardiac electrophysiology 2021-03, Vol.60 (2), p.175-182
Hauptverfasser: Dulai, Rajdip, Sulke, Neil, Furniss, Stephen, Veasey, Rick A.
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container_issue 2
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container_title Journal of interventional cardiac electrophysiology
container_volume 60
creator Dulai, Rajdip
Sulke, Neil
Furniss, Stephen
Veasey, Rick A.
description Background Second-generation cryoballoon ablation is safe and effective in patients with persistent atrial fibrillation (AF). The aim of this study is to report the real long-term AF burden and freedom from AF post-cryoablation using continuous monitoring, and to assess whether intraoperative confirmation of pulmonary vein isolation using electrical mapping is necessary. Methods A total of 33 patients (mean age 75.7 ± 5.6 years, 16 men) with persistent AF who underwent second-generation cryoablation without electrical mapping were reviewed. All patients had a cardiac implantable device and were followed up for a mean of 755 ± 170 days. Results AF burden significantly decreased from 67.51% ± 34.90% to 18.28% ± 26.65% at 1-year follow-up, and this reduction was maintained at final follow-up (18.26% ± 23.70%, p  
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The aim of this study is to report the real long-term AF burden and freedom from AF post-cryoablation using continuous monitoring, and to assess whether intraoperative confirmation of pulmonary vein isolation using electrical mapping is necessary. Methods A total of 33 patients (mean age 75.7 ± 5.6 years, 16 men) with persistent AF who underwent second-generation cryoablation without electrical mapping were reviewed. All patients had a cardiac implantable device and were followed up for a mean of 755 ± 170 days. Results AF burden significantly decreased from 67.51% ± 34.90% to 18.28% ± 26.65% at 1-year follow-up, and this reduction was maintained at final follow-up (18.26% ± 23.70%, p  &lt; 0.001). Continuous monitoring revealed a freedom from AF rate of 33% and 24% at 1-year and full follow-up, respectively. Patients who remained in persistent AF at final follow-up had a trend towards higher pre-ablation AF burden (81.6% ± 29.7% vs 57.3% ± 36.4%, p  = 0.08). Conclusion Second-generation cryoablation without confirming pulmonary vein isolation using electrical mapping is effective leading to significant reductions in AF burden based on continuous beat-to-beat monitoring at 1-year and long-term follow-up.</description><identifier>ISSN: 1383-875X</identifier><identifier>EISSN: 1572-8595</identifier><identifier>DOI: 10.1007/s10840-020-00721-1</identifier><identifier>PMID: 32147799</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Ablation ; Cardiology ; Fibrillation ; Mapping ; Medicine ; Medicine &amp; Public Health ; Monitoring</subject><ispartof>Journal of interventional cardiac electrophysiology, 2021-03, Vol.60 (2), p.175-182</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-8f36c9050e6642eda9c4ab44e47196849e68a9c1f0c0c3e619b4dbe65de9a7b23</citedby><cites>FETCH-LOGICAL-c375t-8f36c9050e6642eda9c4ab44e47196849e68a9c1f0c0c3e619b4dbe65de9a7b23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10840-020-00721-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10840-020-00721-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32147799$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dulai, Rajdip</creatorcontrib><creatorcontrib>Sulke, Neil</creatorcontrib><creatorcontrib>Furniss, Stephen</creatorcontrib><creatorcontrib>Veasey, Rick A.</creatorcontrib><title>The effect of second-generation cryoablation without electrical mapping in persistent AF using continuous monitoring</title><title>Journal of interventional cardiac electrophysiology</title><addtitle>J Interv Card Electrophysiol</addtitle><addtitle>J Interv Card Electrophysiol</addtitle><description>Background Second-generation cryoballoon ablation is safe and effective in patients with persistent atrial fibrillation (AF). The aim of this study is to report the real long-term AF burden and freedom from AF post-cryoablation using continuous monitoring, and to assess whether intraoperative confirmation of pulmonary vein isolation using electrical mapping is necessary. Methods A total of 33 patients (mean age 75.7 ± 5.6 years, 16 men) with persistent AF who underwent second-generation cryoablation without electrical mapping were reviewed. All patients had a cardiac implantable device and were followed up for a mean of 755 ± 170 days. Results AF burden significantly decreased from 67.51% ± 34.90% to 18.28% ± 26.65% at 1-year follow-up, and this reduction was maintained at final follow-up (18.26% ± 23.70%, p  &lt; 0.001). Continuous monitoring revealed a freedom from AF rate of 33% and 24% at 1-year and full follow-up, respectively. Patients who remained in persistent AF at final follow-up had a trend towards higher pre-ablation AF burden (81.6% ± 29.7% vs 57.3% ± 36.4%, p  = 0.08). Conclusion Second-generation cryoablation without confirming pulmonary vein isolation using electrical mapping is effective leading to significant reductions in AF burden based on continuous beat-to-beat monitoring at 1-year and long-term follow-up.</description><subject>Ablation</subject><subject>Cardiology</subject><subject>Fibrillation</subject><subject>Mapping</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Monitoring</subject><issn>1383-875X</issn><issn>1572-8595</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kU1rFjEUhYNYbK3-ARcScONmbL4zWZbSqlBw04K7kMncaVNmkjHJIP335u1UBRcuQnIPzz33koPQO0o-UUL0WaGkF6QjrB2iGe3oC3RCpWZdL4182d68512v5fdj9LqUB0KIIUy9QsecUaG1MSeo3twDhmkCX3GacAGf4tjdQYTsakgR-_yY3DDvxc9Q79NWMcyNz8G7GS9uXUO8wyHiFXIJpUKs-PwKb-UgN7sa4pa2gpcUQ025qW_Q0eTmAm-f71N0e3V5c_Glu_72-evF-XXnuZa16yeuvCGSgFKCweiMF24QAoSmRvXCgOqbRifiieegqBnEOICSIxinB8ZP0cfdd83pxwal2iUUD_PsIrSNLGtjJDGciYZ--Ad9SFuObTvLhJHUCKlMo9hO-ZxKyTDZNYfF5UdLiT1kYvdMbMvEPmViaWt6_2y9DQuMf1p-h9AAvgNlPfwO5L-z_2P7C0-1mRc</recordid><startdate>20210301</startdate><enddate>20210301</enddate><creator>Dulai, Rajdip</creator><creator>Sulke, Neil</creator><creator>Furniss, Stephen</creator><creator>Veasey, Rick A.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20210301</creationdate><title>The effect of second-generation cryoablation without electrical mapping in persistent AF using continuous monitoring</title><author>Dulai, Rajdip ; Sulke, Neil ; Furniss, Stephen ; Veasey, Rick A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-8f36c9050e6642eda9c4ab44e47196849e68a9c1f0c0c3e619b4dbe65de9a7b23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Ablation</topic><topic>Cardiology</topic><topic>Fibrillation</topic><topic>Mapping</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Monitoring</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dulai, Rajdip</creatorcontrib><creatorcontrib>Sulke, Neil</creatorcontrib><creatorcontrib>Furniss, Stephen</creatorcontrib><creatorcontrib>Veasey, Rick A.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of interventional cardiac electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dulai, Rajdip</au><au>Sulke, Neil</au><au>Furniss, Stephen</au><au>Veasey, Rick A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of second-generation cryoablation without electrical mapping in persistent AF using continuous monitoring</atitle><jtitle>Journal of interventional cardiac electrophysiology</jtitle><stitle>J Interv Card Electrophysiol</stitle><addtitle>J Interv Card Electrophysiol</addtitle><date>2021-03-01</date><risdate>2021</risdate><volume>60</volume><issue>2</issue><spage>175</spage><epage>182</epage><pages>175-182</pages><issn>1383-875X</issn><eissn>1572-8595</eissn><abstract>Background Second-generation cryoballoon ablation is safe and effective in patients with persistent atrial fibrillation (AF). The aim of this study is to report the real long-term AF burden and freedom from AF post-cryoablation using continuous monitoring, and to assess whether intraoperative confirmation of pulmonary vein isolation using electrical mapping is necessary. Methods A total of 33 patients (mean age 75.7 ± 5.6 years, 16 men) with persistent AF who underwent second-generation cryoablation without electrical mapping were reviewed. All patients had a cardiac implantable device and were followed up for a mean of 755 ± 170 days. Results AF burden significantly decreased from 67.51% ± 34.90% to 18.28% ± 26.65% at 1-year follow-up, and this reduction was maintained at final follow-up (18.26% ± 23.70%, p  &lt; 0.001). Continuous monitoring revealed a freedom from AF rate of 33% and 24% at 1-year and full follow-up, respectively. Patients who remained in persistent AF at final follow-up had a trend towards higher pre-ablation AF burden (81.6% ± 29.7% vs 57.3% ± 36.4%, p  = 0.08). Conclusion Second-generation cryoablation without confirming pulmonary vein isolation using electrical mapping is effective leading to significant reductions in AF burden based on continuous beat-to-beat monitoring at 1-year and long-term follow-up.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>32147799</pmid><doi>10.1007/s10840-020-00721-1</doi><tpages>8</tpages></addata></record>
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subjects Ablation
Cardiology
Fibrillation
Mapping
Medicine
Medicine & Public Health
Monitoring
title The effect of second-generation cryoablation without electrical mapping in persistent AF using continuous monitoring
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