Four-Step Access to the Sesquiterpene Natural Product Presilphiperfolan-1β-ol and Unnatural Derivatives via Supramolecular Catalysis

Terpenes constitute one of the most structurally varied classes of natural products. A wide range of these structures are produced in nature by type I terpene cyclase enzymes from one single substrate. However, such reactivity has proven difficult to reproduce in solution with man-made systems. Here...

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Veröffentlicht in:Journal of the American Chemical Society 2020-03, Vol.142 (12), p.5894-5900
Hauptverfasser: Syntrivanis, Leonidas-Dimitrios, Némethová, Ivana, Schmid, Dario, Levi, Shani, Prescimone, Alessandro, Bissegger, Fabian, Major, Dan T, Tiefenbacher, Konrad
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Sprache:eng
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