Experimental verification the electron return effect around spherical air cavities for the MR‐Linac using Monte Carlo calculation
Purpose Dose deposition around unplanned air cavities during magnetic resonance‐guided radiotherapy (MRgRT) is influenced by the electron return effect (ERE). This is clinically relevant for gas forming close to or inside organs at risk (OARs) that lie in the path of a single beam, for example, inte...
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Veröffentlicht in: | Medical physics (Lancaster) 2020-06, Vol.47 (6), p.2506-2515 |
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creator | Shortall, J. Vasquez Osorio, E. Aitkenhead, A. Berresford, J. Agnew, J. Budgell, G. Chuter, R. McWilliam, A. Kirkby, K. Mackay, R. Herk, M. |
description | Purpose
Dose deposition around unplanned air cavities during magnetic resonance‐guided radiotherapy (MRgRT) is influenced by the electron return effect (ERE). This is clinically relevant for gas forming close to or inside organs at risk (OARs) that lie in the path of a single beam, for example, intestinal track during pelvic treatment. This work aims to verify Monte Carlo calculations that predict the dosimetric effects of ERE around air cavities. For this, we use GafChromic EBT3 film inside poly‐methyl methacrylate (PMMA) –air phantoms.
Method
Four PMMA phantoms were produced. Three of the phantoms contained centrally located spherical air cavities (0.5, 3.5, 7.5 cm diameter), and one phantom contained no air. The phantoms were split to sandwich GafChromic EBT3 film in the center. The phantoms were irradiated on an Elekta Unity system using a single 10 × 10 cm2 7‐MV photon beam under the influence of a 1.5‐T transverse magnetic field. The measurements were replicated using the Elekta Monaco treatment planning system (TPS). Gamma analysis with pass criteria 3%/3 mm was used to compare the measured and calculated dose distributions. We also consider 3%/2 mm, 2%/3 mm, and 2%/2 mm pass criteria for interest.
Results
The gamma analysis showed that >95% of the points agreed between the TPS‐calculated and measured dose distributions, using 3%/3 mm criteria. The phantom containing the largest air cavity had the lowest agreement, with most of the disagreeing points lying inside the air cavity (dose to air region).
Conclusions
The dose effects due to ERE around spherical air cavities are being calculated in the TPS with sufficient accuracy for clinical use. |
doi_str_mv | 10.1002/mp.14123 |
format | Article |
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Dose deposition around unplanned air cavities during magnetic resonance‐guided radiotherapy (MRgRT) is influenced by the electron return effect (ERE). This is clinically relevant for gas forming close to or inside organs at risk (OARs) that lie in the path of a single beam, for example, intestinal track during pelvic treatment. This work aims to verify Monte Carlo calculations that predict the dosimetric effects of ERE around air cavities. For this, we use GafChromic EBT3 film inside poly‐methyl methacrylate (PMMA) –air phantoms.
Method
Four PMMA phantoms were produced. Three of the phantoms contained centrally located spherical air cavities (0.5, 3.5, 7.5 cm diameter), and one phantom contained no air. The phantoms were split to sandwich GafChromic EBT3 film in the center. The phantoms were irradiated on an Elekta Unity system using a single 10 × 10 cm2 7‐MV photon beam under the influence of a 1.5‐T transverse magnetic field. The measurements were replicated using the Elekta Monaco treatment planning system (TPS). Gamma analysis with pass criteria 3%/3 mm was used to compare the measured and calculated dose distributions. We also consider 3%/2 mm, 2%/3 mm, and 2%/2 mm pass criteria for interest.
Results
The gamma analysis showed that >95% of the points agreed between the TPS‐calculated and measured dose distributions, using 3%/3 mm criteria. The phantom containing the largest air cavity had the lowest agreement, with most of the disagreeing points lying inside the air cavity (dose to air region).
Conclusions
The dose effects due to ERE around spherical air cavities are being calculated in the TPS with sufficient accuracy for clinical use.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1002/mp.14123</identifier><identifier>PMID: 32145087</identifier><language>eng</language><publisher>United States</publisher><subject>cancer ; dose ; Electrons ; experimental dosimetry ; IGRT ; Image‐guided radiotherapy ; Monte Carlo Method ; MRgRT ; MR‐guided radiotherapy ; Particle Accelerators ; Phantoms, Imaging ; Radiotherapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted</subject><ispartof>Medical physics (Lancaster), 2020-06, Vol.47 (6), p.2506-2515</ispartof><rights>2020 American Association of Physicists in Medicine</rights><rights>2020 American Association of Physicists in Medicine.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4213-84908206a39b40178b7de1a8dad63aa8ce1ca1432089633f8c7fdc3611a6dd643</citedby><cites>FETCH-LOGICAL-c4213-84908206a39b40178b7de1a8dad63aa8ce1ca1432089633f8c7fdc3611a6dd643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmp.14123$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmp.14123$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32145087$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shortall, J.</creatorcontrib><creatorcontrib>Vasquez Osorio, E.</creatorcontrib><creatorcontrib>Aitkenhead, A.</creatorcontrib><creatorcontrib>Berresford, J.</creatorcontrib><creatorcontrib>Agnew, J.</creatorcontrib><creatorcontrib>Budgell, G.</creatorcontrib><creatorcontrib>Chuter, R.</creatorcontrib><creatorcontrib>McWilliam, A.</creatorcontrib><creatorcontrib>Kirkby, K.</creatorcontrib><creatorcontrib>Mackay, R.</creatorcontrib><creatorcontrib>Herk, M.</creatorcontrib><title>Experimental verification the electron return effect around spherical air cavities for the MR‐Linac using Monte Carlo calculation</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>Purpose
Dose deposition around unplanned air cavities during magnetic resonance‐guided radiotherapy (MRgRT) is influenced by the electron return effect (ERE). This is clinically relevant for gas forming close to or inside organs at risk (OARs) that lie in the path of a single beam, for example, intestinal track during pelvic treatment. This work aims to verify Monte Carlo calculations that predict the dosimetric effects of ERE around air cavities. For this, we use GafChromic EBT3 film inside poly‐methyl methacrylate (PMMA) –air phantoms.
Method
Four PMMA phantoms were produced. Three of the phantoms contained centrally located spherical air cavities (0.5, 3.5, 7.5 cm diameter), and one phantom contained no air. The phantoms were split to sandwich GafChromic EBT3 film in the center. The phantoms were irradiated on an Elekta Unity system using a single 10 × 10 cm2 7‐MV photon beam under the influence of a 1.5‐T transverse magnetic field. The measurements were replicated using the Elekta Monaco treatment planning system (TPS). Gamma analysis with pass criteria 3%/3 mm was used to compare the measured and calculated dose distributions. We also consider 3%/2 mm, 2%/3 mm, and 2%/2 mm pass criteria for interest.
Results
The gamma analysis showed that >95% of the points agreed between the TPS‐calculated and measured dose distributions, using 3%/3 mm criteria. The phantom containing the largest air cavity had the lowest agreement, with most of the disagreeing points lying inside the air cavity (dose to air region).
Conclusions
The dose effects due to ERE around spherical air cavities are being calculated in the TPS with sufficient accuracy for clinical use.</description><subject>cancer</subject><subject>dose</subject><subject>Electrons</subject><subject>experimental dosimetry</subject><subject>IGRT</subject><subject>Image‐guided radiotherapy</subject><subject>Monte Carlo Method</subject><subject>MRgRT</subject><subject>MR‐guided radiotherapy</subject><subject>Particle Accelerators</subject><subject>Phantoms, Imaging</subject><subject>Radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy Planning, Computer-Assisted</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMlKJEEQhhMZ0XYBn2DIo5fSyKVrOUqjzkA3iui5iM6K0hyyFjOrXG4DvoDPOE9i2q3iZU6RkXz_F_AzdiDgSADI46Y_ElpItcEmUmcq0RKKH2wCUOhEaphus50Q_gBAqqawxbaVFHoKeTZhL6dPPXnbUDug4w_xWVuDg-1aPtwRJ0dm8HHxNIy-5VTX8YOj78a24qG_iwETg2g9N_hgB0uB151fhRdX__6-zm2Lho_Btrd80bUD8Rl610XamdGtLu2xzRpdoP2Puctuzk6vZ7-S-cX579nJPDFaCpXkuoBcQoqqWGoQWb7MKhKYV1ilCjE3JAwKrSTkRapUnZusroxKhcC0qlKtdtnh2tv77n6kMJSNDYacw5a6MZRSZVrpqfiOGt-F4Kku-1gS-udSQPleedn05aryiP78sI7Lhqov8LPjCCRr4NE6ev6vqFxcroVvHZOMTg</recordid><startdate>202006</startdate><enddate>202006</enddate><creator>Shortall, J.</creator><creator>Vasquez Osorio, E.</creator><creator>Aitkenhead, A.</creator><creator>Berresford, J.</creator><creator>Agnew, J.</creator><creator>Budgell, G.</creator><creator>Chuter, R.</creator><creator>McWilliam, A.</creator><creator>Kirkby, K.</creator><creator>Mackay, R.</creator><creator>Herk, M.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202006</creationdate><title>Experimental verification the electron return effect around spherical air cavities for the MR‐Linac using Monte Carlo calculation</title><author>Shortall, J. ; Vasquez Osorio, E. ; Aitkenhead, A. ; Berresford, J. ; Agnew, J. ; Budgell, G. ; Chuter, R. ; McWilliam, A. ; Kirkby, K. ; Mackay, R. ; Herk, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4213-84908206a39b40178b7de1a8dad63aa8ce1ca1432089633f8c7fdc3611a6dd643</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>cancer</topic><topic>dose</topic><topic>Electrons</topic><topic>experimental dosimetry</topic><topic>IGRT</topic><topic>Image‐guided radiotherapy</topic><topic>Monte Carlo Method</topic><topic>MRgRT</topic><topic>MR‐guided radiotherapy</topic><topic>Particle Accelerators</topic><topic>Phantoms, Imaging</topic><topic>Radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy Planning, Computer-Assisted</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shortall, J.</creatorcontrib><creatorcontrib>Vasquez Osorio, E.</creatorcontrib><creatorcontrib>Aitkenhead, A.</creatorcontrib><creatorcontrib>Berresford, J.</creatorcontrib><creatorcontrib>Agnew, J.</creatorcontrib><creatorcontrib>Budgell, G.</creatorcontrib><creatorcontrib>Chuter, R.</creatorcontrib><creatorcontrib>McWilliam, A.</creatorcontrib><creatorcontrib>Kirkby, K.</creatorcontrib><creatorcontrib>Mackay, R.</creatorcontrib><creatorcontrib>Herk, M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shortall, J.</au><au>Vasquez Osorio, E.</au><au>Aitkenhead, A.</au><au>Berresford, J.</au><au>Agnew, J.</au><au>Budgell, G.</au><au>Chuter, R.</au><au>McWilliam, A.</au><au>Kirkby, K.</au><au>Mackay, R.</au><au>Herk, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Experimental verification the electron return effect around spherical air cavities for the MR‐Linac using Monte Carlo calculation</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2020-06</date><risdate>2020</risdate><volume>47</volume><issue>6</issue><spage>2506</spage><epage>2515</epage><pages>2506-2515</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><abstract>Purpose
Dose deposition around unplanned air cavities during magnetic resonance‐guided radiotherapy (MRgRT) is influenced by the electron return effect (ERE). This is clinically relevant for gas forming close to or inside organs at risk (OARs) that lie in the path of a single beam, for example, intestinal track during pelvic treatment. This work aims to verify Monte Carlo calculations that predict the dosimetric effects of ERE around air cavities. For this, we use GafChromic EBT3 film inside poly‐methyl methacrylate (PMMA) –air phantoms.
Method
Four PMMA phantoms were produced. Three of the phantoms contained centrally located spherical air cavities (0.5, 3.5, 7.5 cm diameter), and one phantom contained no air. The phantoms were split to sandwich GafChromic EBT3 film in the center. The phantoms were irradiated on an Elekta Unity system using a single 10 × 10 cm2 7‐MV photon beam under the influence of a 1.5‐T transverse magnetic field. The measurements were replicated using the Elekta Monaco treatment planning system (TPS). Gamma analysis with pass criteria 3%/3 mm was used to compare the measured and calculated dose distributions. We also consider 3%/2 mm, 2%/3 mm, and 2%/2 mm pass criteria for interest.
Results
The gamma analysis showed that >95% of the points agreed between the TPS‐calculated and measured dose distributions, using 3%/3 mm criteria. The phantom containing the largest air cavity had the lowest agreement, with most of the disagreeing points lying inside the air cavity (dose to air region).
Conclusions
The dose effects due to ERE around spherical air cavities are being calculated in the TPS with sufficient accuracy for clinical use.</abstract><cop>United States</cop><pmid>32145087</pmid><doi>10.1002/mp.14123</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
subjects | cancer dose Electrons experimental dosimetry IGRT Image‐guided radiotherapy Monte Carlo Method MRgRT MR‐guided radiotherapy Particle Accelerators Phantoms, Imaging Radiotherapy Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted |
title | Experimental verification the electron return effect around spherical air cavities for the MR‐Linac using Monte Carlo calculation |
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