IQGAP1/ERK regulates fear memory formation via histone posttranslational modifications induced by HDAC2

•IQGAP1 was involved in fear memory.•IQGAP1/ERK mediated histone posttranslational modifications and memory formation via HDAC2.•IQGAP1−/− mice exhibited decreased histone phosphorylation and acetylation. Epigenetic mechanisms of learning and memory are particularly interesting topics in neuroscienc...

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Veröffentlicht in:	Neurobiology of learning and memory 2020-05, Vol.171, p.107210-107210, Article 107210
Hauptverfasser:	Liu, Xiao-Ya, Yao, Bin, Hao, Jing-Ru, Jin, Lu, Gao, Ya, Yang, Xiu, Liu, Le, Sun, Xiao-Yu, Sun, Nan, Gao, Can
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation ERK1/2 Fear memory GluN2A HDAC2 IQGAP1
Online-Zugang:	Volltext
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